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PSMA4 proteasome 20S subunit alpha 4 [ Pan troglodytes (chimpanzee) ]

Gene ID: 453569, updated on 17-Aug-2024

Summary

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Official Symbol
PSMA4provided by VGNC
Official Full Name
proteasome 20S subunit alpha 4provided by VGNC
Primary source
VGNC:VGNC:1894
See related
Ensembl:ENSPTRG00000007345
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See PSMA4 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 16 NC_072414.2 (70487306..70496365)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 15 NC_072413.1 (70462395..70471220)

Chromosome 16 - NC_072414.2Genomic Context describing neighboring genes Neighboring gene iron responsive element binding protein 2 Neighboring gene hydroxylysine kinase Neighboring gene cholinergic receptor nicotinic alpha 5 subunit Neighboring gene cholinergic receptor nicotinic alpha 3 subunit Neighboring gene uncharacterized LOC134808575 Neighboring gene cholinergic receptor nicotinic beta 4 subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in proteasomal protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of proteasome core complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of proteasome core complex, alpha-subunit complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proteasome subunit alpha type-4
Names
proteasome (prosome, macropain) subunit, alpha type, 4
proteasome alpha 4 subunit
proteasome subunit alpha 4
XP_001150431.1
XP_001151019.1
XP_063650327.1
XP_063650328.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072414.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    70487306..70496365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001151019.6 → XP_001151019.1  proteasome subunit alpha type-4 isoform X1

    See identical proteins and their annotated locations for XP_001151019.1

    UniProtKB/TrEMBL
    H2Q9W6
    Related
    ENSPTRP00000012552.5
    Conserved Domains (1) summary
    cd03752
    Location:3 → 216
    proteasome_alpha_type_4; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

  2. XM_001150431.6 → XP_001150431.1  proteasome subunit alpha type-4 isoform X2

    See identical proteins and their annotated locations for XP_001150431.1

    Conserved Domains (1) summary
    cl00467
    Location:1 → 145
    Ntn_hydrolase; The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a ...

  3. XM_063794257.1 → XP_063650327.1  proteasome subunit alpha type-4 isoform X1

    UniProtKB/TrEMBL
    H2Q9W6

  4. XM_063794258.1 → XP_063650328.1  proteasome subunit alpha type-4 isoform X2

Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials