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SAV1 salvador family WW domain containing protein 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 452899, updated on 10-Oct-2024

Summary

Official Symbol
SAV1provided by VGNC
Official Full Name
salvador family WW domain containing protein 1provided by VGNC
Primary source
VGNC:VGNC:12527
Locus tag
CK820_G0002400
See related
Ensembl:ENSPTRG00000006334
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See SAV1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 15 NC_072413.2 (48649663..48685600, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 14 NC_072412.1 (41918816..41957488, complement)

Chromosome 15 - NC_072413.2Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase kinase 5 Neighboring gene small nuclear ribonucleoprotein G-like Neighboring gene atlastin GTPase 1 Neighboring gene zinc finger protein 64-like Neighboring gene ninein Neighboring gene uncharacterized LOC107968165

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables molecular adaptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in hippo signaling IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
protein salvador homolog 1
Names
salvador homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072413.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    48649663..48685600 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016926053.3XP_016781542.1  protein salvador homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8PH54, A0A6D2XQW5, H2Q8A1, K7CA30, K7CT21
    Related
    ENSPTRP00000010732.5
    Conserved Domains (2) summary
    cd00201
    Location:238267
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    pfam00397
    Location:202231
    WW; WW domain
  2. XM_016926054.3XP_016781543.1  protein salvador homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3SA24, K7CT21
    Related
    ENSPTRP00000073884.1
  3. XM_063793378.1XP_063649448.1  protein salvador homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3SA24
  4. XM_016926056.4XP_016781545.1  protein salvador homolog 1 isoform X3

    UniProtKB/TrEMBL
    K7CT21