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pepO endopeptidase PepO [ Streptococcus pseudopneumoniae IS7493 ]

Gene ID: 45218829, updated on 10-Oct-2024

Summary

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Gene symbol
pepO
Gene description
endopeptidase PepO
Locus tag
SPPN_RS07935
Gene type
protein coding
Organism
Streptococcus pseudopneumoniae IS7493 (strain: IS7493)
Lineage
Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Old locus tag
SPPN_08030
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Genomic context

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Sequence:
NC_015875.1 (1544511..1546403, complement)

NC_015875.1Genomic Context describing neighboring genes Neighboring gene LPXTG cell wall anchor domain-containing protein Neighboring gene recombinase family protein Neighboring gene ThiF family adenylyltransferase Neighboring gene MFS transporter Neighboring gene metal ABC transporter ATP-binding protein Neighboring gene metal ABC transporter permease

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_015875.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Endopeptidase PepO Regulates the SpeB Cysteine Protease and Is Essential for the Virulence of Invasive M1T1 Streptococcus pyogenes. Brouwer S, et al. J Bacteriol, 2018 Apr 15. PMID 29378883, Free PMC Article
  2. Streptococcus pneumoniae Endopeptidase O (PepO) Elicits a Strong Innate Immune Response in Mice via TLR2 and TLR4 Signaling Pathways. Zhang H, et al. Front Cell Infect Microbiol, 2016. PMID 26973817, Free PMC Article
  3. Streptococcus pneumoniae endopeptidase O (PepO) is a multifunctional plasminogen- and fibronectin-binding protein, facilitating evasion of innate immunity and invasion of host cells. Agarwal V, et al. J Biol Chem, 2013 Mar 8. PMID 23341464, Free PMC Article
  4. Whole-genome sequence of Streptococcus pseudopneumoniae isolate IS7493. Shahinas D, et al. J Bacteriol, 2011 Nov. PMID 21994930, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
endopeptidase PepO

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_015875.1 Reference assembly

    Range
    1544511..1546403 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_014017316.1 endopeptidase PepO [Streptococcus pseudopneumoniae]

    See identical proteins and their annotated locations for WP_014017316.1

    UniProtKB/TrEMBL
    A0A2N9ZXS9, A0AAN0PZE2
    Conserved Domains (1) summary
    COG3590
    Location:1 → 630
    PepO; Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein
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Gene LinkOut

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