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CYP17A1 cytochrome P450 family 17 subfamily A member 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 450141, updated on 17-Aug-2024

Summary

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Official Symbol
CYP17A1provided by VGNC
Official Full Name
cytochrome P450 family 17 subfamily A member 1provided by VGNC
Primary source
VGNC:VGNC:111834
Locus tag
CK820_G0004060
See related
Ensembl:ENSPTRG00000002900
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
P450c17
Orthologs
human mouse all
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Genomic context

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See CYP17A1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (114932199..114938865, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (105546005..105559764, complement)

Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene sideroflexin 2 Neighboring gene WW domain binding protein 1 like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC107966825 Neighboring gene uncharacterized LOC100612693 Neighboring gene BLOC-1 related complex subunit 7 Neighboring gene arsenite methyltransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species. Arlt W, et al. Endocrinology, 2002 Dec. PMID 12446594
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid 17-alpha-monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in hormone biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in progesterone metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
steroid 17-alpha-hydroxylase/17,20 lyase
Names
17-alpha-hydroxyprogesterone aldolase
CYPXVII
cytochrome P450 17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
cytochrome P450-C17
cytochrome P450c17
steroid 17-alpha-monooxygenase
NP_001009052.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009052.1 → NP_001009052.1  steroid 17-alpha-hydroxylase/17,20 lyase

    See identical proteins and their annotated locations for NP_001009052.1

    Status: PROVISIONAL

    Source sequence(s)
    AF458330
    UniProtKB/Swiss-Prot
    Q8HYN1
    UniProtKB/TrEMBL
    A0A2I3RXX4, A0A2J8PCV9, A0A2J8PCW1
    Related
    ENSPTRP00000069568.1, ENSPTRT00000086417.1
    Conserved Domains (1) summary
    pfam00067
    Location:28 → 493
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    114932199..114938865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8HYN1.1 GenPept UniProtKB/Swiss-Prot:Q8HYN1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials