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arfip2a ADP-ribosylation factor interacting protein 2a [ Danio rerio (zebrafish) ]

Gene ID: 449664, updated on 12-Sep-2024

Summary

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Official Symbol
arfip2aprovided by ZNC
Official Full Name
ADP-ribosylation factor interacting protein 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041010-221
See related
Ensembl:ENSDARG00000059244 AllianceGenome:ZFIN:ZDB-GENE-041010-221
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj35g06; zgc:92579; wu:fj35g06
Summary
Predicted to enable phospholipid binding activity. Predicted to be involved in intracellular protein transport and regulation of Arp2/3 complex-mediated actin nucleation. Predicted to be active in trans-Golgi network membrane. Is expressed in nervous system; neural tube; notochord; polster; and trigeminal placode. Orthologous to human ARFIP2 (ADP ribosylation factor interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See arfip2a in Genome Data Viewer
Location:
chromosome: 15
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (32249071..32267158)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (32391075..32409174)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene BRCA2 DNA repair associated Neighboring gene uncharacterized LOC137487768 Neighboring gene dachsous cadherin-related 1a Neighboring gene FH2 domain containing 4 Neighboring gene tripartite motif containing 3a Neighboring gene complement component 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Highly divergent gene expression programs can lead to similar chordate larval body plans. Sobral D, et al. Curr Biol, 2009 Dec 15. PMID 19931456
  2. Genomic organization and evolution of olfactory receptors and trace amine-associated receptors in channel catfish, Ictalurus punctatus. Gao S, et al. Biochim Biophys Acta Gen Subj, 2017 Mar. PMID 27773705
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein domain specific binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of Arp2/3 complex-mediated actin nucleation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in trans-Golgi network membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
arfaptin-2a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005935.1 → NP_001005935.1  arfaptin-2a

    See identical proteins and their annotated locations for NP_001005935.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083521
    UniProtKB/TrEMBL
    A0A8M1N2K5, Q5XIZ7
    Related
    ENSDARP00000076751.3, ENSDART00000082315.5
    Conserved Domains (1) summary
    cd07660
    Location:173 → 373
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    32249071..32267158
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005157358.5 → XP_005157415.1  arfaptin-2a isoform X1

    UniProtKB/TrEMBL
    A0A8M2B475
    Conserved Domains (1) summary
    cd07660
    Location:192 → 392
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

  2. XM_005157359.5 → XP_005157416.1  arfaptin-2a isoform X2

    UniProtKB/TrEMBL
    A0A8M2B452
    Conserved Domains (1) summary
    cd07660
    Location:171 → 371
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

  3. XM_005157361.5 → XP_005157418.1  arfaptin-2a isoform X4

    UniProtKB/TrEMBL
    A0A8M2B3H5
    Conserved Domains (1) summary
    cd07660
    Location:144 → 344
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

  4. XM_005157360.5 → XP_005157417.1  arfaptin-2a isoform X3

    UniProtKB/TrEMBL
    A0A8M2B3G2, F1QJ24
    Related
    ENSDARP00000123682.2, ENSDART00000133867.4
    Conserved Domains (1) summary
    cd07660
    Location:152 → 352
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin

  5. XM_005157362.5 → XP_005157419.1  arfaptin-2a isoform X5

    UniProtKB/TrEMBL
    A0A8M2B3N8
    Conserved Domains (1) summary
    cd07660
    Location:125 → 325
    BAR_Arfaptin; The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin
Nucleotide Protein
Heading Accession and Version

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