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ACE angiotensin I converting enzyme [ Pan troglodytes (chimpanzee) ]

Gene ID: 449567, updated on 10-Oct-2024

Summary

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Official Symbol
ACEprovided by VGNC
Official Full Name
angiotensin I converting enzymeprovided by VGNC
Primary source
VGNC:VGNC:51632
Locus tag
CK820_G0011626
See related
Ensembl:ENSPTRG00000009513
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
DCP1
Orthologs
human mouse all
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Genomic context

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See ACE in Genome Data Viewer
Location:
chromosome: 19
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (76608656..76629929)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (74793112..74814380)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene cytochrome b561 Neighboring gene peptidyl-prolyl cis-trans isomerase A-like Neighboring gene angiotensin-converting enzyme-like protein Ace3 Neighboring gene potassium voltage-gated channel subfamily H member 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Human-chimpanzee DNA sequence variation in the four major genes of the renin angiotensin system. Dufour C, et al. Genomics, 2000 Oct 1. PMID 11013071

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptidyl-dipeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of systemic arterial blood pressure IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of systemic arterial blood pressure by renin-angiotensin IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
angiotensin-converting enzyme
Names
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
dipeptidyl carboxy peptidase 1 testicular form
dipeptidyl carboxypeptidase I
kininase II
NP_001008995.2
XP_016785978.1
XP_016785979.1
XP_016785980.1
XP_054525730.1
XP_054525731.1
XP_054525732.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008995.3 → NP_001008995.2  angiotensin-converting enzyme precursor

    Status: PROVISIONAL

    Source sequence(s)
    JAQQLN020000019
    UniProtKB/Swiss-Prot
    Q9GLN6, Q9GLN7
    UniProtKB/TrEMBL
    H2QZH0
    Related
    ENSPTRP00000038991.4, ENSPTRT00000049041.4

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    76608656..76629929
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016930490.3 → XP_016785979.1  angiotensin-converting enzyme isoform X2

    UniProtKB/Swiss-Prot
    Q9GLN6, Q9GLN7
    Conserved Domains (1) summary
    pfam01401
    Location:40 → 623
    Peptidase_M2; Angiotensin-converting enzyme

  2. XM_016930489.3 → XP_016785978.1  angiotensin-converting enzyme isoform X1

    UniProtKB/Swiss-Prot
    Q9GLN6, Q9GLN7

  3. XM_054669755.2 → XP_054525730.1  angiotensin-converting enzyme isoform X3

  4. XM_054669757.2 → XP_054525732.1  angiotensin-converting enzyme isoform X6

  5. XM_016930491.2 → XP_016785980.1  angiotensin-converting enzyme isoform X4

    UniProtKB/TrEMBL
    A0A2I3SKE0
    Related
    ENSPTRP00000073589.1
    Conserved Domains (1) summary
    pfam01401
    Location:69 → 647
    Peptidase_M2; Angiotensin-converting enzyme

  6. XM_054669756.1 → XP_054525731.1  angiotensin-converting enzyme isoform X5

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9GLN7.1 GenPept UniProtKB/Swiss-Prot:Q9GLN7

Gene LinkOut

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