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EPRS1 glutamyl-prolyl-tRNA synthetase 1 [ Sus scrofa (pig) ]

Gene ID: 449526, updated on 17-Aug-2024

Summary

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Official Symbol
EPRS1provided by VGNC
Official Full Name
glutamyl-prolyl-tRNA synthetase 1provided by VGNC
Primary source
VGNC:VGNC:96283
See related
Ensembl:ENSSSCG00000010821
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
EPRS
Expression
Ubiquitous expression in ovary (RPKM 25.2), kidney (RPKM 18.9) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See EPRS1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
33
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 10 NC_010452.4 (9579301..9648416, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 10 NC_010452.3 (11663038..11730358, complement)

Chromosome 10 - NC_010452.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110255627 Neighboring gene uncharacterized LOC106507893 Neighboring gene solute carrier family 30 member 10 Neighboring gene uncharacterized LOC102165479 Neighboring gene 3'(2'), 5'-bisphosphate nucleotidase 1 Neighboring gene isoleucyl-tRNA synthetase 2, mitochondrial Neighboring gene microRNA mir-215

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glutamate-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables proline-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutamyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in prolyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of aminoacyl-tRNA synthetase multienzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional glutamate/proline--tRNA ligase
Names
glutaminyl-tRNA synthetase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010452.4 Reference Sscrofa11.1 Primary Assembly

    Range
    9579301..9648416 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021064315.1 → XP_020919974.1  bifunctional glutamate/proline--tRNA ligase isoform X2

    UniProtKB/TrEMBL
    A0A480I033, A0A480K0L8, A0A480T775, A0A480YK74, A0A4X1TS71, A0A8D1XZU8, F1S9K5
    Related
    ENSSSCP00000011535.3, ENSSSCT00000011838.5
    Conserved Domains (3) summary
    PRK08661
    Location:1019 → 1512
    PRK08661; prolyl-tRNA synthetase; Provisional
    cd00936
    Location:753 → 802
    WEPRS_RNA; WEPRS_RNA binding domain. This short RNA-binding domain is found in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is found in multiple copies in eukaryotic bifunctional glutamyl-prolyl-tRNA synthetases (EPRS) in a region that separates ...
    cl27212
    Location:13 → 711
    GlnS; Glutamyl- or glutaminyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]

  2. XM_021064314.1 → XP_020919973.1  bifunctional glutamate/proline--tRNA ligase isoform X1

    UniProtKB/TrEMBL
    A0A286ZQW0, A0A4X1TS76, A0A8D1XVX3
    Related
    ENSSSCP00000034014.1, ENSSSCT00000043477.2
    Conserved Domains (3) summary
    PRK08661
    Location:1026 → 1519
    PRK08661; prolyl-tRNA synthetase; Provisional
    cd00936
    Location:760 → 809
    WEPRS_RNA; WEPRS_RNA binding domain. This short RNA-binding domain is found in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is found in multiple copies in eukaryotic bifunctional glutamyl-prolyl-tRNA synthetases (EPRS) in a region that separates ...
    cl27212
    Location:13 → 718
    GlnS; Glutamyl- or glutaminyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version

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