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mgat2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 448439, updated on 4-Nov-2024

Summary

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Official Symbol
mgat2provided by Xenbase
Official Full Name
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferaseprovided by Xenbase
Primary source
Xenbase:XB-GENE-978789
See related
Ensembl:ENSXETG00000009121 AllianceGenome:Xenbase:XB-GENE-978789
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity and metal ion binding activity. Predicted to act upstream of or within oligosaccharide biosynthetic process and protein glycosylation. Predicted to be located in Golgi membrane and Golgi stack. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIa. Orthologous to human MGAT2 (alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See mgat2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
2
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (93177806..93180580, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (72254896..72257681, complement)

Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene polymerase (DNA directed), epsilon 2, accessory subunit Neighboring gene dynein, axonemal, assembly factor 2 Neighboring gene leucine rich repeat protein 1 Neighboring gene ribosomal protein S29

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC89475

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within oligosaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi stack IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
NP_001006759.1
XP_012823682.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006758.1 → NP_001006759.1  alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

    See identical proteins and their annotated locations for NP_001006759.1

    Status: PROVISIONAL

    Source sequence(s)
    BC075542
    UniProtKB/TrEMBL
    F7E120, Q28HY1, Q6DIJ6
    Related
    ENSXETP00000020003.5, ENSXETT00000020003.5
    Conserved Domains (1) summary
    pfam05060
    Location:79 → 425
    MGAT2; N-acetylglucosaminyltransferase II (MGAT2)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    93177806..93180580 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012968228.3 → XP_012823682.2  alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase isoform X1

    UniProtKB/TrEMBL
    F7E120, Q28HY1, Q6DIJ6
    Related
    ENSXETP00000110677.1, ENSXETT00000120027.1
    Conserved Domains (1) summary
    pfam05060
    Location:79 → 425
    MGAT2; N-acetylglucosaminyltransferase II (MGAT2)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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