rhot2 ras homolog family member T2 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: rhot2provided by Xenbase
Official Full Name: ras homolog family member T2provided by Xenbase
Primary source: Xenbase:XB-GENE-489616
See related: Ensembl:ENSXETG00000003628 AllianceGenome:Xenbase:XB-GENE-489616
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: rasl; arht2; rhot1; miro-2
Summary: Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in mitochondrion organization and mitochondrion transport along microtubule. Predicted to act upstream of or within cellular homeostasis and mitochondrial outer membrane permeabilization. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial outer membrane. Orthologous to human RHOT2 (ras homolog family member T2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	9	NC_030685.2 (14729236..14752139)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	9	NC_030685.1 (9015947..9038858)

Chromosome 9 - NC_030685.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular homeostasis	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within mitochondrial outer membrane permeabilization	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrion organization	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mitochondrion organization	IEA Inferred from Electronic Annotation more info
involved_in mitochondrion transport along microtubule	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mitochondrion transport along microtubule	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in mitochondrial outer membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial outer membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mitochondrial Rho GTPase 2

Names: ras homolog gene family, member T1; ras homolog gene family, member T2

NP_001006725.1

EC 3.6.5.-

XP_017952569.1

EC 3.6.5.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006724.1 → NP_001006725.1 mitochondrial Rho GTPase 2

See identical proteins and their annotated locations for NP_001006725.1

Status: PROVISIONAL

Source sequence(s)

BC075464

UniProtKB/Swiss-Prot

Q6DIS1

UniProtKB/TrEMBL

A0A6I8RJB3, A0A6I8SVI6

Related

ENSXETP00000007838.4, ENSXETT00000007838.5

Conserved Domains (4) summary

cd01892
Location:415 → 590

Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal

cd01893
Location:3 → 169

Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal

pfam08355
Location:341 → 410

EF_assoc_1; EF hand associated

pfam08356
Location:220 → 305

EF_assoc_2; EF hand associated