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Bar Bar [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44798, updated on 28-Dec-2023

Summary

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Gene symbol
Bar
Gene description
Bar
Primary source
FLYBASE:FBgn0000154
See related
AllianceGenome:FB:FBgn0000154
Gene type
unknown
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
B; Bar; BarH1; bar
Summary
Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in imaginal disc-derived leg segmentation and positive regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Genomic context

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Location:
16A1-16A1; 1-57.0 cM

Bibliography

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Related articles in PubMed

  1. THE BAR "GENE" A DUPLICATION. Bridges CB. Science, 1936 Feb 28. PMID 17796454
  2. REVERSE MUTATION OF THE BAR GENE CORRELATED WITH CROSSING OVER. Sturtevant AH, et al. Science, 1923 Jun 29. PMID 17788502
  3. Reduction in Facet Number in Bar-Eyed Drosophila by X-Rays. Luce WM, et al. Genetics, 1951 Sep. PMID 17247361, Free PMC Article
  4. Bar Eye in Drosophila Melanogaster: A Cytological Analysis of Some Mutations and Reverse Mutations. Sutton E. Genetics, 1943 Mar. PMID 17247079, Free PMC Article
  5. The Baroid Mutation in DROSOPHILA MELANOGASTER. Dobzhansky T. Genetics, 1932 Jul. PMID 17246658, Free PMC Article

See all (141) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. homeodomain proteins Bar and Aristaless and the LIM-HOM proteins Apterous and Lim1 regulate distal leg development
    Title: Chip-mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM-HOM proteins Apterous and Lim1 regulate distal leg development.
  2. Data suggest that Bar expression may be temporally regulated through transient inhibition of premature activation of the basal enhancer via specific binding of the Spineless/Tango heterodimer to the negative regulatory motif.
    Title: Temporal regulation of late expression of Bar homeobox genes during Drosophila leg development by Spineless, a homolog of the mammalian dioxin receptor.
Submit: New GeneRIF Correction

General gene information

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Property

  • phenotype only

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in chaeta morphogenesis NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in imaginal disc-derived leg segmentation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in leg disc development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

Gene LinkOut

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