gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gbgt1l3provided by ZNC
Official Full Name: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040912-46
See related: Ensembl:ENSDARG00000035555 AllianceGenome:ZFIN:ZDB-GENE-040912-46
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:101794
Summary: Predicted to enable glycosyltransferase activity. Predicted to be involved in lipid glycosylation. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and vesicle. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; graft-versus-host disease; leukemia (multiple); lung disease (multiple); and severe acute respiratory syndrome. Orthologous to several human genes including GBGT1 (globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)). [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

Location:: chromosome: 5

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (23849647..23870707, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (23345651..23351647, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables glycosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables hexosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in lipid glycosylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in vesicle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3

Names: FS-L3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001004620.1 → NP_001004620.1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3

See identical proteins and their annotated locations for NP_001004620.1

Status: PROVISIONAL

Source sequence(s)

BC081406

UniProtKB/TrEMBL

Q66IC5

Conserved Domains (1) summary

cl11394
Location:75 → 339

Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007116.7 Reference GRCz11 Primary Assembly

Range

23849647..23870707 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021476095.2 → XP_021331770.1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 isoform X1

UniProtKB/TrEMBL

A0A8M9QDS3

Conserved Domains (1) summary

cl11394
Location:80 → 344

Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
XM_068221155.1 → XP_068077256.1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 isoform X2

Related

ENSDARP00000051540.4, ENSDART00000051541.6