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mpdu1a mannose-P-dolichol utilization defect 1a [ Danio rerio (zebrafish) ]

Gene ID: 447806, updated on 2-Nov-2024

Summary

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Official Symbol
mpdu1aprovided by ZNC
Official Full Name
mannose-P-dolichol utilization defect 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040912-9
See related
Ensembl:ENSDARG00000035562 AllianceGenome:ZFIN:ZDB-GENE-040912-9
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mpdu1; zgc:92112
Summary
Predicted to be involved in oligosaccharide biosynthetic process. Predicted to be located in membrane. Is expressed in brain and ventricular zone. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation If. Orthologous to human MPDU1 (mannose-P-dolichol utilization defect 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See mpdu1a in Genome Data Viewer
Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (24177374..24185871)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (23675269..23682071)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 15b Neighboring gene transmembrane 4 L six family member 21a Neighboring gene SRY-box transcription factor 19a Neighboring gene eukaryotic translation initiation factor 4A1B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution. Okuda Y, et al. Dev Dyn, 2006 Mar. PMID 16408288
  2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in oligosaccharide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mannose-P-dolichol utilization defect 1a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004545.1 → NP_001004545.1  mannose-P-dolichol utilization defect 1a

    See identical proteins and their annotated locations for NP_001004545.1

    Status: PROVISIONAL

    Source sequence(s)
    BC081598
    UniProtKB/TrEMBL
    A0A8M1N231, Q66I07
    Related
    ENSDARP00000051551.3, ENSDART00000051552.4
    Conserved Domains (2) summary
    TIGR00951
    Location:44 → 239
    2A43; Lysosomal Cystine Transporter
    pfam04193
    Location:47 → 104
    PQ-loop; PQ loop repeat

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    24177374..24185871
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068221153.1 → XP_068077254.1  mannose-P-dolichol utilization defect 1a isoform X1

  2. XM_068221154.1 → XP_068077255.1  mannose-P-dolichol utilization defect 1a isoform X1

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394575.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    195775..202332
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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