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tpmt.L thiopurine S-methyltransferase L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447769, updated on 17-Aug-2024

Summary

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Official Symbol
tpmt.L
Official Full Name
thiopurine S-methyltransferase L homeolog
Primary source
Xenbase:XB-GENE-941712
Locus tag
XELAEV_18031690mg
See related
EnsemblRapid:ENSXLAG00005017399
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tpmt
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Genomic context

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See tpmt.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (98017210..98041263)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (91253655..91277439)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121394871 Neighboring gene myosin regulatory light chain interacting protein L homeolog Neighboring gene lysine (K)-specific demethylase 1B L homeolog Neighboring gene NHL repeat containing E3 ubiquitin protein ligase 1 L homeolog Neighboring gene kinesin family member 13A L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC84277

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables thiopurine S-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
thiopurine S-methyltransferase L homeolog
NP_001087908.1
XP_018122105.1
XP_018122106.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094439.1 → NP_001087908.1  thiopurine S-methyltransferase L homeolog

    See identical proteins and their annotated locations for NP_001087908.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082459
    UniProtKB/TrEMBL
    Q640Y0
    Conserved Domains (1) summary
    cl17173
    Location:22 → 240
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    98017210..98041263
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018266617.2 → XP_018122106.2  thiopurine S-methyltransferase L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J0VIW5, A0A974HFV9
    Related
    ENSXLAP00005051350.1, ENSXLAT00005052511.1
    Conserved Domains (1) summary
    cl17173
    Location:150 → 364
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  2. XM_018266616.2 → XP_018122105.1  thiopurine S-methyltransferase L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J0VHQ2
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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