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dmap1.L DNA methyltransferase 1 associated protein 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447737, updated on 4-Nov-2024

Summary

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Official Symbol
dmap1.L
Official Full Name
DNA methyltransferase 1 associated protein 1 L homeolog
Primary source
Xenbase:XB-GENE-948176
Locus tag
XELAEV_18023102mg
See related
EnsemblRapid:ENSXLAG00005032807 AllianceGenome:Xenbase:XB-GENE-948176
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
eaf2; swc4; dmap1; meaf2; dnmap1; dnmtap1
Summary
Predicted to enable methyltransferase activity and transcription corepressor activity. Predicted to act upstream of or within several processes, including DNA repair; chromatin remodeling; and negative regulation of transcription by RNA polymerase II. Predicted to be located in chromosome and nucleus. Predicted to be part of NuA4 histone acetyltransferase complex and Swr1 complex. Orthologous to human DMAP1 (DNA methyltransferase 1 associated protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See dmap1.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (86564085..86605595, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (81270240..81311830, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 220, gene 1 L homeolog Neighboring gene ERI1 exoribonuclease family member 3 L homeolog Neighboring gene Kruppel-like factor 17 L homeolog Neighboring gene uncharacterized LOC108714277

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC82015

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA repair IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of NuA4 histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
  
part_of Swr1 complex IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA methyltransferase 1 associated protein 1 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094407.1 → NP_001087876.1  DNA methyltransferase 1 associated protein 1 L homeolog

    See identical proteins and their annotated locations for NP_001087876.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082406
    UniProtKB/TrEMBL
    A0A974D663, Q641D1
    Related
    ENSXLAP00005098507.1, ENSXLAT00005100331.1
    Conserved Domains (2) summary
    pfam05499
    Location:242 → 401
    DMAP1; DNA methyltransferase 1-associated protein 1 (DMAP1)
    pfam16282
    Location:124 → 201
    SANT_DAMP1_like; SANT/Myb-like domain of DAMP1

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    86564085..86605595 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018256842.2 → XP_018112331.1  DNA methyltransferase 1 associated protein 1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974D663, Q641D1
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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