myl9.S myosin light chain 9 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: myl9.S
Official Full Name: myosin light chain 9 S homeolog
Primary source: Xenbase:XB-GENE-17330676
Locus tag: XELAEV_18046588mg
See related: EnsemblRapid:ENSXLAG00005035511 AllianceGenome:Xenbase:XB-GENE-17330676
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary: Predicted to enable calcium ion binding activity. Predicted to act upstream of or within myofibril assembly and platelet aggregation. Predicted to be located in myofibril and stress fiber. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy and megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human MYL9 (myosin light chain 9). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 9_10S

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10S	NC_054388.1 (33571808..33582334)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10S	NC_030741.1 (28076041..28086552)

Chromosome 9_10S - NC_054388.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within myofibril assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within platelet aggregation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in myofibril	IEA Inferred from Electronic Annotation more info
located_in stress fiber	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: myosin light chain 9 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094374.1 → NP_001087843.1 myosin light chain 9 S homeolog

See identical proteins and their annotated locations for NP_001087843.1

Status: PROVISIONAL

Source sequence(s)

BC082366

UniProtKB/TrEMBL

A0A974BT87, Q641H1

Related

ENSXLAP00005106170.1, ENSXLAT00005108245.1

Conserved Domains (2) summary

COG5126
Location:19 → 169

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

cd00051
Location:33 → 77

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...