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pcolce.L procollagen C-endopeptidase enhancer L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447601, updated on 4-Nov-2024

Summary

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Official Symbol
pcolce.L
Official Full Name
procollagen C-endopeptidase enhancer L homeolog
Primary source
Xenbase:XB-GENE-997169
Locus tag
XELAEV_18019519mg
See related
EnsemblRapid:ENSXLAG00005025369 AllianceGenome:Xenbase:XB-GENE-997169
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
pcolce
Summary
Predicted to enable collagen binding activity and peptidase activator activity. Predicted to act upstream of or within proteolysis. Predicted to be located in collagen-containing extracellular matrix and extracellular space. Orthologous to human PCOLCE (procollagen C-endopeptidase enhancer). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pcolce.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (158631685..158644621, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (141574569..141578649, complement)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108710512 Neighboring gene motile sperm domain containing 3 L homeolog Neighboring gene F-box protein 24 L homeolog Neighboring gene leucine-rich repeats and calponin homology (CH) domain containing 4 L homeolog Neighboring gene sialidase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC84811

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables collagen binding IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
procollagen C-endopeptidase enhancer L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094308.1 → NP_001087777.1  procollagen C-endopeptidase enhancer L homeolog precursor

    See identical proteins and their annotated locations for NP_001087777.1

    Status: PROVISIONAL

    Source sequence(s)
    BC081211
    UniProtKB/TrEMBL
    A0A974HUJ0, Q66IT1
    Related
    ENSXLAP00005075501.1, ENSXLAT00005077081.1
    Conserved Domains (2) summary
    cd00041
    Location:155 → 267
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd03576
    Location:355 → 480
    NTR_PCOLCE; NTR domain, PCOLCE subfamily; Procollagen C-endopeptidase enhancers (PCOLCEs) are extracellular matrix proteins that enhance the activity of procollagen C-proteases, by binding to the procollagen I C-peptide. They contain a C-terminal NTR domain, which ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    158631685..158644621 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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