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pnliprp1.S pancreatic lipase-related protein 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447524, updated on 4-Nov-2024

Summary

Official Symbol
pnliprp1.S
Official Full Name
pancreatic lipase-related protein 1 S homeolog
Primary source
Xenbase:XB-GENE-6253766
Locus tag
XELAEV_18036657mg
See related
EnsemblRapid:ENSXLAG00005020548 AllianceGenome:Xenbase:XB-GENE-6253766
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
pnliprp1
Summary
Predicted to enable metal ion binding activity and triacylglycerol lipase activity. Predicted to act upstream of or within lipid catabolic process. Predicted to be located in extracellular space. Orthologous to human PNLIPRP1 (pancreatic lipase related protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See pnliprp1.S in Genome Data Viewer
Location:
chromosome: 7S
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7S NC_054384.1 (2729284..2738724)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7S NC_030737.1 (2761828..2771268)

Chromosome 7S - NC_054384.1Genomic Context describing neighboring genes Neighboring gene inactive pancreatic lipase-related protein 1 Neighboring gene inactive pancreatic lipase-related protein 1 Neighboring gene ventral anterior homeobox 1 S homeolog Neighboring gene heat shock protein family A (Hsp70) member 12A S homeolog

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC83411

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables lipase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables triacylglycerol lipase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
pancreatic lipase-related protein 1 S homeolog
NP_001087700.1
XP_041426455.1
XP_041426456.1
XP_041426457.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094231.1NP_001087700.1  pancreatic lipase-related protein 1 S homeolog precursor

    See identical proteins and their annotated locations for NP_001087700.1

    Status: PROVISIONAL

    Source sequence(s)
    BC081107
    UniProtKB/TrEMBL
    Q642R3
    Related
    ENSXLAP00005060227.1, ENSXLAT00005061676.1
    Conserved Domains (3) summary
    cd00707
    Location:52348
    Pancreat_lipase_like; Pancreatic lipase-like enzymes. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the ...
    cd01759
    Location:355467
    PLAT_PL; PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of ...
    pfam00151
    Location:18352
    Lipase; Lipase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    2729284..2738724
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041570521.1XP_041426455.1  pancreatic lipase-related protein 1 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8FDS7, A0A974CAX0
    Conserved Domains (2) summary
    cd01759
    Location:355467
    PLAT_PL; PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of ...
    pfam00151
    Location:18352
    Lipase
  2. XM_041570523.1XP_041426457.1  pancreatic lipase-related protein 1 S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1LAA7
    Conserved Domains (2) summary
    cd00707
    Location:1241
    Pancreat_lipase_like; Pancreatic lipase-like enzymes. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the ...
    cd01759
    Location:248360
    PLAT_PL; PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of ...
  3. XM_041570522.1XP_041426456.1  pancreatic lipase-related protein 1 S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1LAE0
    Conserved Domains (2) summary
    cd00707
    Location:3282
    Pancreat_lipase_like; Pancreatic lipase-like enzymes. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the ...
    cd01759
    Location:289401
    PLAT_PL; PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of ...