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ppp1r13l.L protein phosphatase 1 regulatory subunit 13 like L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447427, updated on 4-Nov-2024

Summary

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Official Symbol
ppp1r13l.L
Official Full Name
protein phosphatase 1 regulatory subunit 13 like L homeolog
Primary source
Xenbase:XB-GENE-5848627
Locus tag
XELAEV_18039071mg
See related
EnsemblRapid:ENSXLAG00005021973 AllianceGenome:Xenbase:XB-GENE-5848627
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ppp1r13l
Summary
Predicted to enable p53 binding activity. Predicted to act upstream of or within regulation of apoptotic process. Predicted to be located in nucleus. Orthologous to human PPP1R13L (protein phosphatase 1 regulatory subunit 13 like). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ppp1r13l.L in Genome Data Viewer
Location:
chromosome: 8L
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (62704321..62745453)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (49518492..49559625)

Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108698515 Neighboring gene DNA-directed RNA polymerase I subunit RPA34 Neighboring gene excision repair cross-complementation group 2 L homeolog Neighboring gene creatine kinase, M-type L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cell cycle-dependent regulation of Greatwall kinase by protein phosphatase 1 and regulatory subunit 3B. Ren D, et al. J Biol Chem, 2017 Jun 16. PMID 28446604, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC86497

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables p53 binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein phosphatase 1 regulatory subunit 13 like L homeolog
Names
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
protein phosphatase 1, regulatory subunit 13 like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094134.1 → NP_001087603.1  protein phosphatase 1 regulatory subunit 13 like L homeolog

    See identical proteins and their annotated locations for NP_001087603.1

    Status: PROVISIONAL

    Source sequence(s)
    BC080430
    UniProtKB/TrEMBL
    A0A974C792, Q66KF0
    Related
    ENSXLAP00005064601.1, ENSXLAT00005066115.1
    Conserved Domains (4) summary
    cd11952
    Location:739 → 794
    SH3_iASPP; Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP)
    cd00204
    Location:612 → 726
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:609 → 700
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:609 → 635
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    62704321..62745453
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018229041.2 → XP_018084530.1  protein phosphatase 1 regulatory subunit 13 like L homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J0TGV6, A0A974C792
    Related
    ENSXLAP00005064699.1, ENSXLAT00005066213.1

  2. XM_018229040.2 → XP_018084529.1  protein phosphatase 1 regulatory subunit 13 like L homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J0TGV6, A0A974C792
    Related
    ENSXLAP00005064638.1, ENSXLAT00005066152.1

  3. XM_041572070.1 → XP_041428004.1  protein phosphatase 1 regulatory subunit 13 like L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1LG47, A0A974C792
    Conserved Domains (3) summary
    cd11952
    Location:806 → 861
    SH3_iASPP; Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP)
    COG0666
    Location:668 → 795
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:676 → 702
    ANK; ANK repeat [structural motif]

  4. XM_041572071.1 → XP_041428005.1  protein phosphatase 1 regulatory subunit 13 like L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1LH40, A0A974C792
    Conserved Domains (3) summary
    cd11952
    Location:803 → 858
    SH3_iASPP; Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP)
    COG0666
    Location:665 → 792
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:673 → 699
    ANK; ANK repeat [structural motif]

  5. XM_041572072.1 → XP_041428006.1  protein phosphatase 1 regulatory subunit 13 like L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1LF22, A0A974C792
    Related
    ENSXLAP00005064584.1, ENSXLAT00005066098.1
    Conserved Domains (3) summary
    cd11952
    Location:784 → 839
    SH3_iASPP; Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP)
    COG0666
    Location:646 → 773
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:654 → 680
    ANK; ANK repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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