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lhx9.S LIM homeobox 9 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447351, updated on 17-Aug-2024

Summary

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Official Symbol
lhx9.S
Official Full Name
LIM homeobox 9 S homeolog
Primary source
Xenbase:XB-GENE-866119
Locus tag
XELAEV_18025494mg
See related
EnsemblRapid:ENSXLAG00005008322
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
lhx9; XLhx9; lhx9-a; lhx9-b; lhx9.L; lhx9HD; lhx9LIM; lhx9alpha
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Genomic context

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Location:
chromosome: 4S
Exon count:
7
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (90416787..90454120)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (84083788..84117880)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene EEIG family member 2 S homeolog Neighboring gene DENN/MADD domain containing 1B S homeolog Neighboring gene NIMA-related kinase 7 S homeolog Neighboring gene ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Lhx9-integrin pathway is essential for positioning of the proepicardial organ. Tandon P, et al. Development, 2016 Mar 1. PMID 26811386, Free PMC Article
  2. FGF receptor dependent regulation of Lhx9 expression in the developing nervous system. Atkinson-Leadbeater K, et al. Dev Dyn, 2009 Feb. PMID 19161224
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the Lhx9-integrin-paxillin pathway has a role in proepicardial organ positioning and epicardial formation
    Title: The Lhx9-integrin pathway is essential for positioning of the proepicardial organ.
  2. while FGF signalling initiates and maintains brain XLhx9 expression, in the eye primordium the requirement of FGFs for expression is rapidly lost.
    Title: FGF receptor dependent regulation of Lhx9 expression in the developing nervous system.
Submit: New GeneRIF Correction

General gene information

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Homology

Clone Names

  • MGC84078

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within dorsal spinal cord interneuron anterior axon guidance ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
LIM/homeobox protein Lhx9
Names
LIM homeobox 9 L homeolog
LIM homeobox protein 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094058.1 → NP_001087527.1  LIM/homeobox protein Lhx9

    See identical proteins and their annotated locations for NP_001087527.1

    Status: PROVISIONAL

    Source sequence(s)
    BC080067
    UniProtKB/Swiss-Prot
    Q68EY3
    UniProtKB/TrEMBL
    A0A974CZL2
    Conserved Domains (3) summary
    cd09377
    Location:130 → 188
    LIM2_Lhx2_Lhx9; The second LIM domain of Lhx2 and Lhx9 family
    cd09469
    Location:63 → 126
    LIM1_Lhx2; The first LIM domain of Lhx2
    pfam00046
    Location:272 → 313
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    90416787..90454120
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018259656.2 → XP_018115145.1  LIM/homeobox protein Lhx9 isoform X1

    UniProtKB/TrEMBL
    A0A8J0V930, B7U6H6
    Related
    ENSXLAP00005023954.1, ENSXLAT00005024662.1
    Conserved Domains (4) summary
    cd09369
    Location:73 → 126
    LIM1_Lhx2_Lhx9; The first LIM domain of Lhx2 and Lhx9 family
    cd09377
    Location:131 → 189
    LIM2_Lhx2_Lhx9; The second LIM domain of Lhx2 and Lhx9 family
    COG5576
    Location:251 → 379
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:273 → 326
    Homeobox; Homeobox domain

  2. XM_041591358.1 → XP_041447292.1  LIM/homeobox protein Lhx9 isoform X1

    UniProtKB/TrEMBL
    A0A8J0V930, B7U6H6
    Related
    ENSXLAP00005023964.1, ENSXLAT00005024672.1
    Conserved Domains (4) summary
    cd09369
    Location:73 → 126
    LIM1_Lhx2_Lhx9; The first LIM domain of Lhx2 and Lhx9 family
    cd09377
    Location:131 → 189
    LIM2_Lhx2_Lhx9; The second LIM domain of Lhx2 and Lhx9 family
    COG5576
    Location:251 → 379
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:273 → 326
    Homeobox; Homeobox domain

  3. XM_018259657.2 → XP_018115146.1  LIM/homeobox protein Lhx9 isoform X3

    UniProtKB/TrEMBL
    A0A1L8GGI9, A0A974CZV5
    Related
    ENSXLAP00005023969.1, ENSXLAT00005024677.1

  4. XM_041591359.1 → XP_041447293.1  LIM/homeobox protein Lhx9 isoform X2

    UniProtKB/TrEMBL
    A0A8J1N1H3, B7U6H6
    Conserved Domains (4) summary
    cd09369
    Location:73 → 126
    LIM1_Lhx2_Lhx9; The first LIM domain of Lhx2 and Lhx9 family
    cd09377
    Location:130 → 188
    LIM2_Lhx2_Lhx9; The second LIM domain of Lhx2 and Lhx9 family
    smart00389
    Location:268 → 324
    HOX; Homeodomain
    COG5576
    Location:250 → 378
    COG5576; Homeodomain-containing transcription factor [Transcription]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q68EY3.1 GenPept UniProtKB/Swiss-Prot:Q68EY3

Gene LinkOut

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