sfr1.L SWI5-dependent homologous recombination repair protein 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: sfr1.L
Official Full Name: SWI5-dependent homologous recombination repair protein 1 L homeolog
Primary source: Xenbase:XB-GENE-6254016
Locus tag: XELAEV_18034627mg
See related: EnsemblRapid:ENSXLAG00005014495 AllianceGenome:Xenbase:XB-GENE-6254016
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: mei5; sfr1; meir5; c10orf78
Summary: Predicted to enable nuclear receptor coactivator activity. Predicted to act upstream of or within double-strand break repair via homologous recombination. Predicted to be located in nucleus. Predicted to be part of Swi5-Sfr1 complex. Orthologous to human SFR1 (SWI5 dependent homologous recombination repair protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 7L

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7L	NC_054383.1 (22812150..22825619, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7L	NC_030736.1 (22866175..22874374, complement)

Chromosome 7L - NC_054383.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables nuclear receptor coactivator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within double-strand break repair via homologous recombination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within double-strand break repair via homologous recombination	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Swi5-Sfr1 complex	IEA Inferred from Electronic Annotation more info
part_of Swi5-Sfr1 complex	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: swi5-dependent recombination DNA repair protein 1 homolog

Names: MEI5 meiotic recombination protein homolog; MEI5 recombination repair protein homolog; Meiosis protein 5 homolog; SWI5-dependent recombination repair 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094013.1 → NP_001087482.1 swi5-dependent recombination DNA repair protein 1 homolog

See identical proteins and their annotated locations for NP_001087482.1

Status: PROVISIONAL

Source sequence(s)

BC079991

UniProtKB/Swiss-Prot

Q68F53

UniProtKB/TrEMBL

A0A1L8FJ76, A0A974CEC8

Related

ENSXLAP00005042417.1, ENSXLAT00005043484.1

Conserved Domains (1) summary

pfam10376
Location:19 → 204

Mei5; Double-strand recombination repair protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

22812150..22825619 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041568540.1 → XP_041424474.1 swi5-dependent recombination DNA repair protein 1 homolog isoform X1

UniProtKB/Swiss-Prot

Q68F53

UniProtKB/TrEMBL

A0A1L8FJ76, A0A974CEC8

Conserved Domains (1) summary

pfam10376
Location:19 → 204

Mei5; Double-strand recombination repair protein
XM_041568539.1 → XP_041424473.1 swi5-dependent recombination DNA repair protein 1 homolog isoform X1

UniProtKB/Swiss-Prot

Q68F53

UniProtKB/TrEMBL

A0A1L8FJ76, A0A974CEC8

Conserved Domains (1) summary

pfam10376
Location:19 → 204

Mei5; Double-strand recombination repair protein
XM_018224559.2 → XP_018080048.1 swi5-dependent recombination DNA repair protein 1 homolog isoform X1

UniProtKB/Swiss-Prot

Q68F53

UniProtKB/TrEMBL

A0A1L8FJ76, A0A974CEC8

Conserved Domains (1) summary

pfam10376
Location:19 → 204

Mei5; Double-strand recombination repair protein