vps25.L vacuolar protein sorting 25 homolog L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: vps25.L
Official Full Name: vacuolar protein sorting 25 homolog L homeolog
Primary source: Xenbase:XB-GENE-976405
Locus tag: XELAEV_18043826mg
See related: AllianceGenome:Xenbase:XB-GENE-976405
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: derp9; eap20; fap20; vps25
Summary: Predicted to enable protein homodimerization activity and structural molecule activity. Predicted to act upstream of or within protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be located in cytoplasm. Predicted to be part of ESCRT II complex. Orthologous to human VPS25 (vacuolar protein sorting 25 homolog). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 9_10L

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10L	NC_054387.1 (34250900..34258787)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10L	NC_030740.1 (28665511..28673384)

Chromosome 9_10L - NC_054387.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within multivesicular body sorting pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of ESCRT II complex	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: vacuolar protein-sorting-associated protein 25

Names: ESCRT-II complex subunit VPS25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093955.1 → NP_001087424.1 vacuolar protein-sorting-associated protein 25

See identical proteins and their annotated locations for NP_001087424.1

Status: PROVISIONAL

Source sequence(s)

BC079766

UniProtKB/Swiss-Prot

Q6AX45

UniProtKB/TrEMBL

A0A974BTQ9, A0A974H385

Conserved Domains (1) summary

pfam05871
Location:8 → 143

ESCRT-II; ESCRT-II complex subunit