asb5.S ankyrin repeat and SOCS box containing 5 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: asb5.S
Official Full Name: ankyrin repeat and SOCS box containing 5 S homeolog
Primary source: Xenbase:XB-GENE-950781
Locus tag: XELAEV_18009149mg
See related: EnsemblRapid:ENSXLAG00005001071
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: asb5; asb5.L
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Genomic context

Location:: chromosome: 1S

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (36774963..36800279)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (36602774..36628024)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Process	Evidence Code	Pubs
acts_upstream_of_or_within intracellular signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of protein catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ankyrin repeat and SOCS box containing 5 S homeolog

Names: ankyrin repeat and SOCS box containing 5 L homeolog; ankyrin repeat and SOCS box-containing 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093879.1 → NP_001087348.1 ankyrin repeat and SOCS box containing 5 S homeolog

See identical proteins and their annotated locations for NP_001087348.1

Status: PROVISIONAL

Source sequence(s)

BC078595

UniProtKB/TrEMBL

Q66KQ7

Related

ENSXLAP00005003223.1, ENSXLAT00005003285.1

Conserved Domains (4) summary

cd00204
Location:69 → 186

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

cd03724
Location:286 → 327

SOCS_ASB5; SOCS (suppressors of cytokine signaling) box of ASB5-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB5 has been implicated in the initiation of arteriogenesis. The general function of the SOCS ...

pfam12796
Location:72 → 163

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:69 → 98

ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

36774963..36800279

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041575681.1 → XP_041431615.1 ankyrin repeat and SOCS box containing 5 S homeolog isoform X1

UniProtKB/TrEMBL

A0A1L8HLL7, A0A974I0R7

Conserved Domains (3) summary

cd03724
Location:286 → 327

SOCS_ASB5; SOCS (suppressors of cytokine signaling) box of ASB5-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB5 has been implicated in the initiation of arteriogenesis. The general function of the SOCS ...

sd00045
Location:69 → 98

ANK; ANK repeat [structural motif]

cl39094
Location:71 → 271

Ank_2; Ankyrin repeats (3 copies)
XM_041575682.1 → XP_041431616.1 ankyrin repeat and SOCS box containing 5 S homeolog isoform X2

UniProtKB/TrEMBL

A0A8J1LRA0

Related

ENSXLAP00005003222.1, ENSXLAT00005003284.1

Conserved Domains (3) summary

sd00045
Location:39 → 68

ANK; ANK repeat [structural motif]

cl02533
Location:256 → 297

SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...

cl39094
Location:41 → 241

Ank_2; Ankyrin repeats (3 copies)