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pemt.L phosphatidylethanolamine N-methyltransferase L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447155, updated on 4-Nov-2024

Summary

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Official Symbol
pemt.L
Official Full Name
phosphatidylethanolamine N-methyltransferase L homeolog
Primary source
Xenbase:XB-GENE-6078073
Locus tag
XELAEV_18045570mg
See related
EnsemblRapid:ENSXLAG00005026474 AllianceGenome:Xenbase:XB-GENE-6078073
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
pemt
Summary
Predicted to enable phosphatidyl-N-methylethanolamine N-methyltransferase activity and phosphatidylethanolamine N-methyltransferase activity. Predicted to act upstream of or within methylation and phosphatidylcholine biosynthetic process. Predicted to be located in endoplasmic reticulum membrane and mitochondrial membrane. Orthologous to human PEMT (phosphatidylethanolamine N-methyltransferase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pemt.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (122240220..122325570, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (111659000..111744708, complement)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 9 L homeolog Neighboring gene ras related dexamethasone induced 1 L homeolog Neighboring gene uncharacterized LOC121397980 Neighboring gene retinoic acid induced 1 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC85461

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidyl-N-methylethanolamine N-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylethanolamine N-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphatidylcholine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
phosphatidylethanolamine N-methyltransferase L homeolog
NP_001087332.1
XP_018089970.1
XP_041431606.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093863.2 → NP_001087332.1  phosphatidylethanolamine N-methyltransferase L homeolog

    See identical proteins and their annotated locations for NP_001087332.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078570
    UniProtKB/TrEMBL
    Q66KT1
    Related
    ENSXLAP00005078801.1, ENSXLAT00005080394.1
    Conserved Domains (1) summary
    pfam04191
    Location:90 → 188
    PEMT; Phospholipid methyltransferase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    122240220..122325570 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018234481.2 → XP_018089970.1  phosphatidylethanolamine N-methyltransferase L homeolog isoform X1

    UniProtKB/TrEMBL
    Q66KT1
    Related
    ENSXLAP00005078647.1, ENSXLAT00005080237.1

  2. XM_041575672.1 → XP_041431606.1  phosphatidylethanolamine N-methyltransferase L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A1L8EYQ8, A0A974H4R7
    Conserved Domains (1) summary
    pfam04191
    Location:90 → 158
    PEMT; Phospholipid methyltransferase
Nucleotide Protein Strain
Heading Accession and Version

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