cdc42se1.S cdc42 small effector 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: cdc42se1.S
Official Full Name: cdc42 small effector 1 S homeolog
Primary source: Xenbase:XB-GENE-6254352
Locus tag: XELAEV_18042821mg
See related: EnsemblRapid:ENSXLAG00005024523 AllianceGenome:Xenbase:XB-GENE-6254352
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: scip1; spec1; cdc42se1; cdc42se1-a; cdc42se1-b
Summary: Predicted to enable small GTPase binding activity. Predicted to act upstream of or within regulation of Rho protein signal transduction and regulation of cell shape. Predicted to be located in cytoplasm; cytoskeleton; and plasma membrane. Orthologous to human CDC42SE1 (CDC42 small effector 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 8S

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8S	NC_054386.1 (100006913..100041380)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8S	NC_030739.1 (94981848..95016286)

Chromosome 8S - NC_054386.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables small GTPase binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of Rho protein signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of cell shape	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: CDC42 small effector protein 1-A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093813.2 → NP_001087282.1 CDC42 small effector protein 1-A

See identical proteins and their annotated locations for NP_001087282.1

Status: PROVISIONAL

Source sequence(s)

BC078508

UniProtKB/Swiss-Prot

Q66KZ1

UniProtKB/TrEMBL

A0A974C4J7

Related

ENSXLAP00005072858.1, ENSXLAT00005074418.1

Conserved Domains (1) summary

cl00113
Location:28 → 66

CRIB; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...