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pla2g2e.S phospholipase A2 group IIE S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447090, updated on 4-Nov-2024

Summary

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Official Symbol
pla2g2e.S
Official Full Name
phospholipase A2 group IIE S homeolog
Primary source
Xenbase:XB-GENE-5756021
Locus tag
XELAEV_18037502mg
See related
EnsemblRapid:ENSXLAG00005007783 AllianceGenome:Xenbase:XB-GENE-5756021
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
oc22; pla2g2e; otoconin-22
Summary
Predicted to enable calcium ion binding activity; calcium-dependent phospholipase A2 activity; and phospholipid binding activity. Predicted to act upstream of or within arachidonate secretion; lipid catabolic process; and phospholipid metabolic process. Predicted to be located in extracellular region. Orthologous to human PLA2G2E (phospholipase A2 group IIE). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pla2g2e.S in Genome Data Viewer
Location:
chromosome: 7S
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7S NC_054384.1 (80581256..80585020, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7S NC_030737.1 (61552540..61556304, complement)

Chromosome 7S - NC_054384.1Genomic Context describing neighboring genes Neighboring gene C1q and TNF related 12 Neighboring gene ubiquitin conjugating enzyme E2 J2 S homeolog Neighboring gene ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 S homeolog Neighboring gene uncharacterized LOC121396496

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC85254

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium-dependent phospholipase A2 activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phospholipase A2 activity IEA
Inferred from Electronic Annotation
more info
  
enables phospholipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within arachidonate secretion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipid catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phospholipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
phospholipase A2 group IIE S homeolog
Names
phospholipase A2, group IIE
NP_001087269.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093800.2 → NP_001087269.1  phospholipase A2 group IIE S homeolog precursor

    See identical proteins and their annotated locations for NP_001087269.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078486
    UniProtKB/Swiss-Prot
    P41485
    UniProtKB/TrEMBL
    A0A974HA80, Q66L11
    Related
    ENSXLAP00005022268.1, ENSXLAT00005022959.1
    Conserved Domains (1) summary
    cd00125
    Location:23 → 135
    PLA2c; PLA2c: Phospholipase A2, a family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    80581256..80585020 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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