asb12.L ankyrin repeat and SOCS box-containing 12 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: asb12.L
Official Full Name: ankyrin repeat and SOCS box-containing 12 L homeolog
Primary source: Xenbase:XB-GENE-5924802
Locus tag: XELAEV_18038739mg
See related: AllianceGenome:Xenbase:XB-GENE-5924802
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: asb12
Summary: Predicted to enable RNA binding activity and RNA nuclease activity. Predicted to act upstream of or within RNA processing; intracellular signal transduction; and protein ubiquitination. Orthologous to human ASB12 (ankyrin repeat and SOCS box containing 12). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 8L

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8L	NC_054385.1 (37404489..37409350)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8L	NC_030738.1 (24219759..24224640)

Chromosome 8L - NC_054385.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA nuclease activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within intracellular signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein ubiquitination	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: ankyrin repeat and SOCS box-containing 12 L homeolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093794.2 → NP_001087263.1 ankyrin repeat and SOCS box-containing 12 L homeolog

See identical proteins and their annotated locations for NP_001087263.1

Status: PROVISIONAL

Source sequence(s)

BC078478

UniProtKB/TrEMBL

A0A974H773, Q66L19

Conserved Domains (4) summary

cd00204
Location:52 → 179

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

cd03716
Location:253 → 295

SOCS_ASB_like; SOCS (suppressors of cytokine signaling) box of ASB (ankyrin repeat and SOCS box) and SSB (SPRY domain-containing SOCS box proteins) protein families. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence of a variable ...

pfam12796
Location:55 → 146

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:52 → 81

ANK; ANK repeat [structural motif]