gsdme.L gasdermin E L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: gsdme.L
Official Full Name: gasdermin E L homeolog
Primary source: Xenbase:XB-GENE-6254565
Locus tag: XELAEV_18030968mg
See related: AllianceGenome:Xenbase:XB-GENE-6254565
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: dfna5; dfna5.L; icere-1
Summary: Predicted to act upstream of or within programmed cell death. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 5 and sensorineural hearing loss. Orthologous to human GSDME (gasdermin E). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 6L

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	6L	NC_054381.1 (42112795..42122430, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	6L	NC_030734.1 (38313022..38322657, complement)

Chromosome 6L - NC_054381.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Process	Evidence Code	Pubs
acts_upstream_of_or_within programmed cell death	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: gasdermin E L homeolog

Names: deafness, autosomal dominant 5 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093709.1 → NP_001087178.1 gasdermin E L homeolog

See identical proteins and their annotated locations for NP_001087178.1

Status: PROVISIONAL

Source sequence(s)

BC078125

UniProtKB/TrEMBL

Q6DCC3

Conserved Domains (1) summary

pfam04598
Location:1 → 134

Gasdermin; Gasdermin family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

42112795..42122430 complement

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GenBank, FASTA, Sequence Viewer (Graphics)