apba2.L amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: apba2.L
Official Full Name: amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog
Primary source: Xenbase:XB-GENE-952386
Locus tag: XELAEV_18018141mg
See related: EnsemblRapid:ENSXLAG00005026411 AllianceGenome:Xenbase:XB-GENE-952386
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: apba2
Summary: Predicted to enable amyloid-beta binding activity. Predicted to act upstream of or within chemical synaptic transmission. Predicted to be located in cytoplasm; dendritic spine; and plasma membrane. Orthologous to human APBA2 (amyloid beta precursor protein binding family A member 2). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 3L

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3L	NC_054375.1 (102594617..102704101)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3L	NC_030728.1 (87294084..87403652)

Chromosome 3L - NC_054375.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables amyloid-beta binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within chemical synaptic transmission	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in dendritic spine	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093697.1 → NP_001087166.1 amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog

See identical proteins and their annotated locations for NP_001087166.1

Status: PROVISIONAL

Source sequence(s)

BC078109

UniProtKB/TrEMBL

A0A974DEK9, Q6DCD8

Related

ENSXLAP00005078951.1, ENSXLAT00005080542.1

Conserved Domains (3) summary

cd00992
Location:646 → 712

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd01208
Location:364 → 524

PTB_X11; X11-like Phosphotyrosine-binding (PTB) domain

pfam00595
Location:557 → 638

PDZ; PDZ domain (Also known as DHR or GLGF)