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guk1.L guanylate kinase 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447035, updated on 4-Nov-2024

Summary

Official Symbol
guk1.L
Official Full Name
guanylate kinase 1 L homeolog
Primary source
Xenbase:XB-GENE-6254574
Locus tag
XELAEV_18030584mg
See related
EnsemblRapid:ENSXLAG00005036220 AllianceGenome:Xenbase:XB-GENE-6254574
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
gmk; guk1
Summary
Predicted to enable ATP binding activity and guanylate kinase activity. Predicted to act upstream of or within phosphorylation and purine nucleotide metabolic process. Predicted to be located in cytosol. Is expressed in dermal system and ectoderm. Orthologous to human GUK1 (guanylate kinase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See guk1.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (8495266..8519201)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (6034849..6059387)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene chromosome 6 C1orf35 homolog L homeolog Neighboring gene mitochondrial ribosomal protein L55 L homeolog Neighboring gene obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF L homeolog Neighboring gene meiosis-specific coiled-coil domain-containing protein MEIOC

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC82941

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables guanylate kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within purine nucleotide metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
guanylate kinase 1 L homeolog
NP_001087146.1
XP_018122067.1
XP_018122069.1
XP_018122071.1
XP_041421435.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093677.1NP_001087146.1  guanylate kinase 1 L homeolog

    See identical proteins and their annotated locations for NP_001087146.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078071
    UniProtKB/TrEMBL
    A0A974HDB8, Q6AZF5
    Related
    ENSXLAP00005108302.1, ENSXLAT00005110461.1
    Conserved Domains (1) summary
    TIGR03263
    Location:5185
    guanyl_kin; guanylate kinase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    8495266..8519201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018266580.2XP_018122069.1  guanylate kinase 1 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A974HDB8, Q6AZF5
    Conserved Domains (1) summary
    TIGR03263
    Location:5185
    guanyl_kin; guanylate kinase
  2. XM_018266578.2XP_018122067.1  guanylate kinase 1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8FUZ6, A0A974CL28, A0A974HDB8
    Related
    ENSXLAP00005108305.1, ENSXLAT00005110464.1
  3. XM_018266582.1XP_018122071.1  guanylate kinase 1 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A974HDB8, Q6AZF5
    Conserved Domains (1) summary
    TIGR03263
    Location:5185
    guanyl_kin; guanylate kinase
  4. XM_041565501.1XP_041421435.1  guanylate kinase 1 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A974HDB8, Q6AZF5
    Conserved Domains (1) summary
    TIGR03263
    Location:5185
    guanyl_kin; guanylate kinase