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asb15.L ankyrin repeat and SOCS box containing 15 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447004, updated on 4-Nov-2024

Summary

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Official Symbol
asb15.L
Official Full Name
ankyrin repeat and SOCS box containing 15 L homeolog
Primary source
Xenbase:XB-GENE-1014024
Locus tag
XELAEV_18017672mg
See related
EnsemblRapid:ENSXLAG00005026017 AllianceGenome:Xenbase:XB-GENE-1014024
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
asb15
Summary
Predicted to enable transcription cis-regulatory region binding activity. Predicted to act upstream of or within intracellular signal transduction; positive regulation of transcription by RNA polymerase II; and protein ubiquitination. Predicted to be located in nucleus. Orthologous to human ASB15 (ankyrin repeat and SOCS box containing 15). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See asb15.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (76844532..76864297)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (61518323..61538571)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene IQ motif and ubiquitin domain containing L homeolog Neighboring gene NADH:ubiquinone oxidoreductase subunit A5 L homeolog Neighboring gene leiomodin 2 L homeolog Neighboring gene WASP like actin nucleation promoting factor L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC82431

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables transcription cis-regulatory region binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ankyrin repeat and SOCS box containing 15 L homeolog
Names
ankyrin repeat and SOCS box-containing 15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093646.1 → NP_001087115.1  ankyrin repeat and SOCS box containing 15 L homeolog

    See identical proteins and their annotated locations for NP_001087115.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078003
    UniProtKB/TrEMBL
    Q6DCL0
    Related
    ENSXLAP00005077298.1, ENSXLAT00005078889.1
    Conserved Domains (5) summary
    cd00204
    Location:168 → 293
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03731
    Location:529 → 584
    SOCS_ASB15; SOCS (suppressors of cytokine signaling) box of ASB15-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. Human ASB15 is expressed predominantly in skeletal muscle and participates in the regulation of ...
    pfam12796
    Location:179 → 270
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:276 → 325
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:175 → 204
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    76844532..76864297
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018251036.2 → XP_018106525.1  ankyrin repeat and SOCS box containing 15 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8GYX5, A0A974DDK6
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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