arhgap30.S Rho GTPase activating protein 30 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: arhgap30.S
Official Full Name: Rho GTPase activating protein 30 S homeolog
Primary source: Xenbase:XB-GENE-5915775
Locus tag: XELAEV_18043038mg
See related: EnsemblRapid:ENSXLAG00005006420 AllianceGenome:Xenbase:XB-GENE-5915775
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: arhgap30
Summary: Predicted to enable GTPase activator activity. Predicted to act upstream of or within small GTPase-mediated signal transduction. Orthologous to human ARHGAP30 (Rho GTPase activating protein 30). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 8S

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8S	NC_054386.1 (103873147..103895551, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8S	NC_030739.1 (98850581..98873082, complement)

Chromosome 8S - NC_054386.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within small GTPase-mediated signal transduction	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Rho GTPase activating protein 30 S homeolog; rho GTPase activating protein 30 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093552.1 → NP_001087021.1 Rho GTPase activating protein 30 S homeolog

See identical proteins and their annotated locations for NP_001087021.1

Status: PROVISIONAL

Source sequence(s)

BC077906

UniProtKB/TrEMBL

A0A974C5A0, Q6DCT7

Related

ENSXLAP00005019070.1, ENSXLAT00005019405.1

Conserved Domains (1) summary

cd04384
Location:19 → 213

RhoGAP_CdGAP; RhoGAP_CdGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

103873147..103895551 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041574239.1 → XP_041430173.1 rho GTPase activating protein 30 S homeolog isoform X1

UniProtKB/TrEMBL

A0A8J1LKS5, A0A974C5A0

Conserved Domains (1) summary

cl02570
Location:3 → 77

RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...