cyba.L cytochrome b-245 alpha polypeptide L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: cyba.L
Official Full Name: cytochrome b-245 alpha polypeptide L homeolog
Primary source: Xenbase:XB-GENE-959421
Locus tag: XELAEV_18022707mg
See related: EnsemblRapid:ENSXLAG00005016356 AllianceGenome:Xenbase:XB-GENE-959421
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: cyba; p22-phox
Summary: Predicted to enable heme binding activity; metal ion binding activity; and oxidoreductase activity. Predicted to be located in plasma membrane. Predicted to be part of NADPH oxidase complex. Human ortholog(s) of this gene implicated in artery disease (multiple); asthma; chronic obstructive pulmonary disease; and phagocyte bactericidal dysfunction (multiple). Orthologous to human CYBA (cytochrome b-245 alpha chain). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 4L

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4L	NC_054377.1 (60905384..60917176, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4L	NC_030730.1 (55686955..55698748, complement)

Chromosome 4L - NC_054377.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of NADPH oxidase complex	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytochrome b-245 alpha polypeptide L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093549.1 → NP_001087018.1 cytochrome b-245 alpha polypeptide L homeolog

See identical proteins and their annotated locations for NP_001087018.1

Status: PROVISIONAL

Source sequence(s)

BC077902

UniProtKB/TrEMBL

A0A974D2X8, Q6AZJ1

Related

ENSXLAP00005048174.1, ENSXLAT00005049289.1

Conserved Domains (1) summary

pfam05038
Location:9 → 186

Cytochrom_B558a; Cytochrome Cytochrome b558 alpha-subunit

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

60905384..60917176 complement

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GenBank, FASTA, Sequence Viewer (Graphics)