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apbb1.L amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446838, updated on 4-Nov-2024

Summary

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Official Symbol
apbb1.L
Official Full Name
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog
Primary source
Xenbase:XB-GENE-5762058
Locus tag
XELAEV_18013992mg
See related
EnsemblRapid:ENSXLAG00005013220 AllianceGenome:Xenbase:XB-GENE-5762058
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
fe65; apbb1
Summary
Predicted to enable amyloid-beta binding activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See apbb1.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (190478364..190493286, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (174105747..174121105)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100126633 Neighboring gene E3 ubiquitin-protein ligase TRIM8 Neighboring gene uncharacterized LOC108708791 Neighboring gene hemopexin L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC80654

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables amyloid-beta binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093534.1 → NP_001087003.1  amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog

    See identical proteins and their annotated locations for NP_001087003.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077881
    UniProtKB/TrEMBL
    A0A974I040, Q6DCV8
    Related
    ENSXLAP00005039040.1, ENSXLAT00005039961.1
    Conserved Domains (3) summary
    cd01271
    Location:437 → 561
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cd01272
    Location:279 → 409
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain
    pfam00397
    Location:184 → 212
    WW; WW domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    190478364..190493286 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018245141.2 → XP_018100630.1  amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J0UC97, A0A974I040
    Related
    ENSXLAP00005039009.1, ENSXLAT00005039930.1

  2. XM_018245140.2 → XP_018100629.1  amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J0UC97, A0A974I040
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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