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epcam.S epithelial cell adhesion molecule S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446810, updated on 4-Nov-2024

Summary

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Official Symbol
epcam.S
Official Full Name
epithelial cell adhesion molecule S homeolog
Primary source
Xenbase:XB-GENE-986672
Locus tag
XELAEV_18028769mg
See related
EnsemblRapid:ENSXLAG00005026102 AllianceGenome:Xenbase:XB-GENE-986672
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
epcam; epcam-a; epcam-b; tacstd1
Summary
Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital diarrhea 5 with tufting enteropathy and hereditary nonpolyposis colorectal cancer type 8. Orthologous to human EPCAM (epithelial cell adhesion molecule). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See epcam.S in Genome Data Viewer
Location:
chromosome: 5S
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5S NC_054380.1 (22566953..22573255)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5S NC_030733.1 (22631735..22638039)

Chromosome 5S - NC_054380.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene uncharacterized LOC108717393 Neighboring gene potassium channel, two pore domain subfamily K, member 12 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The tumor-associated EpCAM regulates morphogenetic movements through intracellular signaling. Maghzal N, et al. J Cell Biol, 2010 Nov 1. PMID 20974811, Free PMC Article
  2. Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress. Wang F, et al. Sci Rep, 2018 Feb 8. PMID 29422626, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. identification of EpCAM in a gain-of-function screen for inducers of abnormal tissue mixing during gastrulation
    Title: The tumor-associated EpCAM regulates morphogenetic movements through intracellular signaling.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC80540

Gene Ontology Provided by Xenbase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
epithelial cell adhesion molecule S homeolog
Names
tumor-associated calcium signal transducer 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093506.1 → NP_001086975.1  epithelial cell adhesion molecule S homeolog

    See identical proteins and their annotated locations for NP_001086975.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077845
    UniProtKB/TrEMBL
    A0A974CS18, Q6DCY7
    Related
    ENSXLAP00005077586.1, ENSXLAT00005079177.1
    Conserved Domains (1) summary
    cd00191
    Location:54 → 114
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054380.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    22566953..22573255
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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