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hmbox1.L homeobox containing 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446787, updated on 4-Nov-2024

Summary

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Official Symbol
hmbox1.L
Official Full Name
homeobox containing 1 L homeolog
Primary source
Xenbase:XB-GENE-6254831
Locus tag
XELAEV_18028253mg
See related
EnsemblRapid:ENSXLAG00005010001 AllianceGenome:Xenbase:XB-GENE-6254831
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
pbhnf; hmbox1; hnf1la; hmbox1-a; hmbox1-b
Summary
Predicted to enable double-stranded telomeric DNA binding activity. Predicted to act upstream of or within positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human HMBOX1 (homeobox containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See hmbox1.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (163531179..163583321, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (152491975..152545507, complement)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene methionine sulfoxide reductase A, gene 1 L homeolog Neighboring gene kinesin family member 13B L homeolog Neighboring gene uncharacterized LOC108717245 Neighboring gene integrator complex subunit 9-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC80451, MGC81685

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables double-stranded telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
homeobox containing 1 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093483.1 → NP_001086952.1  homeobox containing 1 L homeolog isoform 2

    See identical proteins and their annotated locations for NP_001086952.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077815
    UniProtKB/TrEMBL
    A0A974CXY1, Q6DD14
    Related
    ENSXLAP00005029478.1, ENSXLAT00005030224.1
    Conserved Domains (2) summary
    cd00086
    Location:255 → 327
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam04814
    Location:14 → 212
    HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N terminus

  2. NM_001093630.1 → NP_001087099.1  homeobox containing 1 L homeolog isoform 1

    See identical proteins and their annotated locations for NP_001087099.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077394
    UniProtKB/TrEMBL
    A0A974CXY1, Q6DDW0

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    163531179..163583321 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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