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med18.S mediator complex subunit 18 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446768, updated on 4-Nov-2024

Summary

Official Symbol
med18.S
Official Full Name
mediator complex subunit 18 S homeolog
Primary source
Xenbase:XB-GENE-6255351
Locus tag
XELAEV_18015087mg
See related
EnsemblRapid:ENSXLAG00005008430 AllianceGenome:Xenbase:XB-GENE-6255351
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
med18
Summary
Predicted to enable transcription coregulator activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II and termination of RNA polymerase II transcription. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Orthologous to human MED18 (mediator complex subunit 18). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See med18.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (68263543..68266416)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (63889910..63892789)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene FGR proto-oncogene, Src family tyrosine kinase S homeolog Neighboring gene sestrin 2 S homeolog Neighboring gene uncharacterized LOC121400577 Neighboring gene phosphatase and actin regulator 4 S homeolog

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC80383

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of core mediator complex IEA
Inferred from Electronic Annotation
more info
 
part_of mediator complex IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mediator of RNA polymerase II transcription subunit 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093464.1NP_001086933.1  mediator of RNA polymerase II transcription subunit 18

    See identical proteins and their annotated locations for NP_001086933.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077790
    UniProtKB/Swiss-Prot
    Q6DD39
    UniProtKB/TrEMBL
    A0A974DN31, A0A974HVS5
    Related
    ENSXLAP00005024320.1, ENSXLAT00005025028.1
    Conserved Domains (1) summary
    pfam09637
    Location:19205
    Med18; Med18 protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    68263543..68266416
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)