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orc6.L origin recognition complex subunit 6 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446747, updated on 4-Nov-2024

Summary

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Official Symbol
orc6.L
Official Full Name
origin recognition complex subunit 6 L homeolog
Primary source
Xenbase:XB-GENE-6255358
Locus tag
XELAEV_18022776mg
See related
AllianceGenome:Xenbase:XB-GENE-6255358
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
orc6; orc6l
Summary
Predicted to enable DNA binding activity. Predicted to act upstream of or within DNA replication initiation. Predicted to be located in nucleus. Predicted to be part of nuclear origin of replication recognition complex. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 3. Orthologous to human ORC6 (origin recognition complex subunit 6). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See orc6.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (66437013..66443565, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (61220205..61226898, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene chromosome 4 C16orf87 homolog L homeolog Neighboring gene UPF0547 protein C16orf87 homolog Neighboring gene myosin light chain kinase 3 L homeolog Neighboring gene VPS35 retromer complex component L homeolog Neighboring gene histamine H3 receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC78925

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA replication IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within DNA replication initiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of nuclear origin of replication recognition complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
origin recognition complex subunit 6 L homeolog
Names
origin recognition complex, subunit 6 like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093443.1 → NP_001086912.1  origin recognition complex subunit 6 L homeolog

    See identical proteins and their annotated locations for NP_001086912.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077746
    UniProtKB/TrEMBL
    A0A974D2X7, Q6AZK1
    Conserved Domains (2) summary
    cd11583
    Location:94 → 186
    Orc6_mid; Middle domain of the origin recognition complex subunit 6
    pfam05460
    Location:6 → 94
    ORC6; Origin recognition complex subunit 6 (ORC6)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    66437013..66443565 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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