tbc1d31.L TBC1 domain family member 31 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: tbc1d31.L
Official Full Name: TBC1 domain family member 31 L homeolog
Primary source: Xenbase:XB-GENE-969771
Locus tag: XELAEV_18032337mg
See related: EnsemblRapid:ENSXLAG00005007740 AllianceGenome:Xenbase:XB-GENE-969771
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: wdr67; tbc1d31
Summary: Predicted to enable molecular adaptor activity. Predicted to act upstream of or within cilium assembly. Predicted to be located in centriolar satellite and ciliary basal body. Is expressed in ectoderm and nervous system. Orthologous to human TBC1D31 (TBC1 domain family member 31). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 6L

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	6L	NC_054381.1 (150593516..150627546)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	6L	NC_030734.1 (141426966..141461172)

Chromosome 6L - NC_054381.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables molecular adaptor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell projection organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cilium assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in centriolar satellite	IEA Inferred from Electronic Annotation more info
located_in centriolar satellite	ISS Inferred from Sequence or Structural Similarity more info
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in centrosome	ISS Inferred from Sequence or Structural Similarity more info
located_in ciliary basal body	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: TBC1 domain family member 31

Names: TBC1 domain family, member 31; WD repeat domain 67; WD repeat-containing protein 67

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093396.1 → NP_001086865.1 TBC1 domain family member 31

See identical proteins and their annotated locations for NP_001086865.1

Status: PROVISIONAL

Source sequence(s)

BC077576

UniProtKB/Swiss-Prot

Q6DDI6

Related

ENSXLAP00005022122.1, ENSXLAT00005022814.1

Conserved Domains (6) summary

COG2319
Location:42 → 362

WD40; WD40 repeat [General function prediction only]

sd00039
Location:46 → 81

7WD40; WD40 repeat [structural motif]

cd16269
Location:766 → 781

GBP_C; coiled coil [structural motif]

cl02495
Location:477 → 628

RabGAP-TBC; Rab-GTPase-TBC domain

cl02567
Location:46 → 334

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

cl20817
Location:701 → 809

GBP_C; Guanylate-binding protein, C-terminal domain