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triobp.L TRIO and F-actin binding protein L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446692, updated on 4-Nov-2024

Summary

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Official Symbol
triobp.L
Official Full Name
TRIO and F-actin binding protein L homeolog
Primary source
Xenbase:XB-GENE-866161
Locus tag
XELAEV_18023706mg
See related
EnsemblRapid:ENSXLAG00005026400 AllianceGenome:Xenbase:XB-GENE-866161
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tara; triobp
Summary
Predicted to enable actin filament binding activity. Predicted to act upstream of or within positive regulation of substrate adhesion-dependent cell spreading. Predicted to be located in actin cytoskeleton. Is expressed in ectoderm; genital system; urinary system; and visual system. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 28. Orthologous to human TRIOBP (TRIO and F-actin binding protein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See triobp.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (120744065..120774020, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (115423711..115473531, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene glycine C-acetyltransferase L homeolog Neighboring gene H1.0 linker histone L homeolog Neighboring gene serine/arginine repetitive matrix protein 2-like Neighboring gene ArfGAP with dual PH domains 1 like L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC83528

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
TRIO and F-actin binding protein L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093388.1 → NP_001086857.1  TRIO and F-actin binding protein L homeolog

    See identical proteins and their annotated locations for NP_001086857.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077563
    UniProtKB/TrEMBL
    A0A974D5K2, Q6DDJ6
    Related
    ENSXLAP00005078630.1, ENSXLAT00005080221.1
    Conserved Domains (3) summary
    cd13275
    Location:9 → 110
    PH_M-RIP; Myosin phosphatase-RhoA Interacting Protein Pleckstrin homology (PH) domain
    pfam00169
    Location:9 → 102
    PH; PH domain
    cl24005
    Location:360 → 448
    DUF2570; Protein of unknown function (DUF2570)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    120744065..120774020 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041589333.1 → XP_041445267.1  TRIO and F-actin binding protein L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1MU36
    Related
    ENSXLAP00005078807.1, ENSXLAT00005080398.1
    Conserved Domains (2) summary
    COG1196
    Location:250 → 524
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13275
    Location:11 → 112
    PH_M-RIP; Myosin phosphatase-RhoA Interacting Protein Pleckstrin homology (PH) domain
Nucleotide Protein Strain
Heading Accession and Version

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