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agbl5.L AGBL carboxypeptidase 5 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446690, updated on 4-Nov-2024

Summary

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Official Symbol
agbl5.L
Official Full Name
AGBL carboxypeptidase 5 L homeolog
Primary source
Xenbase:XB-GENE-958773
Locus tag
XELAEV_18039245mg
See related
EnsemblRapid:ENSXLAG00005022649 AllianceGenome:Xenbase:XB-GENE-958773
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ccp5; agbl5
Summary
Predicted to enable metallocarboxypeptidase activity and zinc ion binding activity. Predicted to act upstream of or within protein deglutamylation and proteolysis. Predicted to be located in several cellular components, including cytosol; midbody; and spindle. Human ortholog(s) of this gene implicated in retinitis pigmentosa 75. Orthologous to human AGBL5 (AGBL carboxypeptidase 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See agbl5.L in Genome Data Viewer
Location:
chromosome: 8L
Exon count:
19
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (67591727..67621249, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (54098577..54129181, complement)

Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene loricrin Neighboring gene valyl-tRNA synthetase 2, mitochondrial L homeolog Neighboring gene zinc finger protein 615 Neighboring gene zinc finger protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC83526

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables metallocarboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein deglutamylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in midbody IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in spindle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
AGBL carboxypeptidase 5 L homeolog; cytosolic carboxypeptidase-like protein 5
Names
ATP/GTP binding protein-like 5 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    67591727..67621249 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041572916.1 → XP_041428850.1  cytosolic carboxypeptidase-like protein 5

    UniProtKB/TrEMBL
    A0A1L8F8R1, A0A974C7N5
    Related
    ENSXLAP00005066682.1, ENSXLAT00005068206.1
    Conserved Domains (2) summary
    cd06236
    Location:180 → 613
    M14_AGBL5_like; Peptidase M14-like domain of ATP/GTP binding protein (AGBL)-5 and related proteins
    pfam18027
    Location:10 → 150
    Pepdidase_M14_N; Cytosolic carboxypeptidase N-terminal domain

  2. XM_018228986.2 → XP_018084475.1  cytosolic carboxypeptidase-like protein 5

    UniProtKB/TrEMBL
    A0A1L8F8R1, A0A974C7N5
    Conserved Domains (2) summary
    cd06236
    Location:180 → 613
    M14_AGBL5_like; Peptidase M14-like domain of ATP/GTP binding protein (AGBL)-5 and related proteins
    pfam18027
    Location:10 → 150
    Pepdidase_M14_N; Cytosolic carboxypeptidase N-terminal domain

  3. XM_018228987.2 → XP_018084476.1  cytosolic carboxypeptidase-like protein 5

    UniProtKB/TrEMBL
    A0A1L8F8R1, A0A974C7N5
    Conserved Domains (2) summary
    cd06236
    Location:180 → 613
    M14_AGBL5_like; Peptidase M14-like domain of ATP/GTP binding protein (AGBL)-5 and related proteins
    pfam18027
    Location:10 → 150
    Pepdidase_M14_N; Cytosolic carboxypeptidase N-terminal domain

  4. XM_018228988.2 → XP_018084477.1  cytosolic carboxypeptidase-like protein 5

    UniProtKB/TrEMBL
    A0A1L8F8R1, A0A974C7N5
    Conserved Domains (2) summary
    cd06236
    Location:180 → 613
    M14_AGBL5_like; Peptidase M14-like domain of ATP/GTP binding protein (AGBL)-5 and related proteins
    pfam18027
    Location:10 → 150
    Pepdidase_M14_N; Cytosolic carboxypeptidase N-terminal domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001093386.1: Suppressed sequence

    Description
    NM_001093386.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

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