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cyb5a.L cytochrome b5 type A (microsomal) L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446542, updated on 4-Nov-2024

Summary

Official Symbol
cyb5a.L
Official Full Name
cytochrome b5 type A (microsomal) L homeolog
Primary source
Xenbase:XB-GENE-959307
Locus tag
XELAEV_18031783mg
See related
EnsemblRapid:ENSXLAG00005010261 AllianceGenome:Xenbase:XB-GENE-959307
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cyb5a
Summary
Predicted to enable heme binding activity and metal ion binding activity. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in methemoglobinemia and methemoglobinemia and ambiguous genitalia. Orthologous to human CYB5A (cytochrome b5 type A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See cyb5a.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (106202163..106224704)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (99263614..99286367)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene divergent protein kinase domain 1C L homeolog Neighboring gene CNDP dipeptidase 2 (metallopeptidase M20 family) L homeolog Neighboring gene traf2 and NCK-interacting protein kinase-like L homeolog Neighboring gene F-box only protein 15-like

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC80327

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cytochrome b5 type A (microsomal) L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093238.1NP_001086707.1  cytochrome b5 type A (microsomal) L homeolog

    See identical proteins and their annotated locations for NP_001086707.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077334
    UniProtKB/TrEMBL
    A0A974HG04, Q6DE13
    Related
    ENSXLAP00005030242.1, ENSXLAT00005030999.1
    Conserved Domains (1) summary
    pfam00173
    Location:982
    Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    106202163..106224704
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)