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aktip.L AKT interacting protein L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446528, updated on 4-Nov-2024

Summary

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Official Symbol
aktip.L
Official Full Name
AKT interacting protein L homeolog
Primary source
Xenbase:XB-GENE-6255939
Locus tag
XELAEV_18022762mg
See related
EnsemblRapid:ENSXLAG00005015740 AllianceGenome:Xenbase:XB-GENE-6255939
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
fts; aktip; fts-A; aktip-a; aktip-b
Summary
Predicted to act upstream of or within several processes, including early endosome to late endosome transport; endosome organization; and endosome to lysosome transport. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of FHF complex. Orthologous to human AKTIP (AKT interacting protein). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See aktip.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (65495447..65516525, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (60273345..60294489, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene P2X purinoceptor 7-like Neighboring gene uncharacterized LOC108714127 Neighboring gene nedd4 binding protein 1 L homeolog Neighboring gene phosphorylase kinase, beta L homeolog Neighboring gene integrin alpha FG-GAP repeat containing 1 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC80257, MGC115456

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within early endosome to late endosome transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within endosome organization ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within endosome to lysosome transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within lysosome organization ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of FHF complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
AKT-interacting protein homolog A
Names
fused toes homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093224.1 → NP_001086693.1  AKT-interacting protein homolog A

    See identical proteins and their annotated locations for NP_001086693.1

    Status: PROVISIONAL

    Source sequence(s)
    BC100233
    UniProtKB/Swiss-Prot
    Q498F8, Q6DE27
    UniProtKB/TrEMBL
    A0A974D4S0
    Related
    ENSXLAP00005046498.1, ENSXLAT00005047602.1
    Conserved Domains (2) summary
    smart00212
    Location:80 → 222
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic domain homologues
    COG5078
    Location:80 → 220
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    65495447..65516525 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q498F8.1 GenPept UniProtKB/Swiss-Prot:Q498F8

Gene LinkOut

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