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arf6.2.L ADP ribosylation factor 6 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446512, updated on 4-Nov-2024

Summary

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Official Symbol
arf6.2.L
Official Full Name
ADP ribosylation factor 6 L homeolog
Primary source
Xenbase:XB-GENE-967364
Locus tag
XELAEV_18039639mg
See related
EnsemblRapid:ENSXLAG00005017408 AllianceGenome:Xenbase:XB-GENE-967364
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
arf6.L
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to act upstream of or within several processes, including intracellular protein transport; protein localization to endosome; and regulation of dendritic spine development. Predicted to be located in several cellular components, including Flemming body; cytoplasmic vesicle; and filopodium membrane. Orthologous to human ARF6 (ADP ribosylation factor 6). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See arf6.2.L in Genome Data Viewer
Location:
chromosome: 8L
Exon count:
1
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (85425220..85428634, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (70740777..70744191, complement)

Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene MAM domain containing glycosylphosphatidylinositol anchor 2 L homeolog Neighboring gene valosin containing protein lysine methyltransferase L homeolog Neighboring gene galectin 3 like L homeolog Neighboring gene proteasome 26S subunit, ATPase 6 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. XGAP, an ArfGAP, is required for polarized localization of PAR proteins and cell polarity in Xenopus gastrulation. Hyodo-Miura J, et al. Dev Cell, 2006 Jul. PMID 16824954
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC80156

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein localization to endosome IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of dendritic spine development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Flemming body IEA
Inferred from Electronic Annotation
more info
  
located_in cleavage furrow IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in endocytic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in filopodium membrane IEA
Inferred from Electronic Annotation
more info
  
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in recycling endosome membrane IEA
Inferred from Electronic Annotation
more info
  
located_in ruffle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ADP ribosylation factor 6 L homeolog
Names
ADP-ribosylation factor 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093208.1 → NP_001086677.1  ADP ribosylation factor 6 L homeolog

    See identical proteins and their annotated locations for NP_001086677.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077296
    UniProtKB/TrEMBL
    A0A974C220, A0A974C988, Q5EAX8, Q6DE46
    Related
    ENSXLAP00005051379.1, ENSXLAT00005052541.1
    Conserved Domains (2) summary
    TIGR00231
    Location:13 → 157
    small_GTP; small GTP-binding protein domain
    cl21455
    Location:1 → 175
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    85425220..85428634 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials