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gars1.L glycyl-tRNA synthetase 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446482, updated on 4-Nov-2024

Summary

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Official Symbol
gars1.L
Official Full Name
glycyl-tRNA synthetase 1 L homeolog
Primary source
Xenbase:XB-GENE-963086
Locus tag
XELAEV_18030618mg
See related
EnsemblRapid:ENSXLAG00005027949 AllianceGenome:Xenbase:XB-GENE-963086
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
gars; gars.L
Summary
Predicted to enable ATP binding activity; glycine-tRNA ligase activity; and transferase activity. Predicted to act upstream of or within mitochondrial glycyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2D and autosomal dominant distal hereditary motor neuronopathy 5. Orthologous to human GARS1 (glycyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See gars1.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
17
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (10612999..10641165, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (8153348..8181719, complement)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene proteasome maturation protein L homeolog Neighboring gene corticotropin releasing hormone receptor 2 L homeolog Neighboring gene integumentary mucin C.1-like Neighboring gene CTD small phosphatase like L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC79076

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity, acting on a tRNA IEA
Inferred from Electronic Annotation
more info
  
enables glycine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within glycyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mitochondrial glycyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tRNA aminoacylation for protein translation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glycyl-tRNA synthetase 1 L homeolog
Names
glycyl-tRNA synthetase L homeolog
NP_001086647.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093178.1 → NP_001086647.1  glycyl-tRNA synthetase 1 L homeolog

    See identical proteins and their annotated locations for NP_001086647.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077232
    UniProtKB/TrEMBL
    A0A974HEZ2, Q6DEA1
    Related
    ENSXLAP00005083047.1, ENSXLAT00005084685.1
    Conserved Domains (1) summary
    PLN02734
    Location:68 → 733
    PLN02734; glycyl-tRNA synthetase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    10612999..10641165 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
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