stx11.S syntaxin 11 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: stx11.S
Official Full Name: syntaxin 11 S homeolog
Primary source: Xenbase:XB-GENE-952019
Locus tag: XELAEV_18028969mg
See related: EnsemblRapid:ENSXLAG00005008231 AllianceGenome:Xenbase:XB-GENE-952019
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: stx11
Summary: Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to act upstream of or within intracellular protein transport; synaptic vesicle fusion to presynaptic active zone membrane; and vesicle docking. Predicted to be located in presynaptic active zone membrane and synaptic vesicle. Predicted to be part of SNARE complex. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 4. Orthologous to human STX11 (syntaxin 11). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 5S

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	5S	NC_054380.1 (36690690..36708119)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	5S	NC_030733.1 (36565810..36583219)

Chromosome 5S - NC_054380.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables SNAP receptor activity	IEA Inferred from Electronic Annotation more info
enables SNARE binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within exocytosis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within synaptic vesicle fusion to presynaptic active zone membrane	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vesicle docking	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of SNARE complex	IEA Inferred from Electronic Annotation more info
located_in endomembrane system	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in presynaptic active zone membrane	IEA Inferred from Electronic Annotation more info
located_in synaptic vesicle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: syntaxin 11 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093177.1 → NP_001086646.1 syntaxin 11 S homeolog

See identical proteins and their annotated locations for NP_001086646.1

Status: PROVISIONAL

Source sequence(s)

BC077231

UniProtKB/TrEMBL

A0A974CR51, Q6DEA2

Related

ENSXLAP00005023675.1, ENSXLAT00005024381.1

Conserved Domains (3) summary

cd00179
Location:39 → 191

SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...

cd15878
Location:201 → 263

SNARE_syntaxin11; SNARE motif of syntaxin 11

pfam00804
Location:39 → 236

Syntaxin; Syntaxin