spire1.S spire-type actin nucleation factor 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: spire1.S
Official Full Name: spire-type actin nucleation factor 1 S homeolog
Primary source: Xenbase:XB-GENE-5955266
Locus tag: XELAEV_18046219mg
See related: EnsemblRapid:ENSXLAG00005030839 AllianceGenome:Xenbase:XB-GENE-5955266
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: pEg6; spire; spire1; spire2; spire1.L
Summary: Predicted to enable actin binding activity. Predicted to act upstream of or within several processes, including Golgi vesicle transport; cytoskeleton organization; and cytoskeleton-dependent cytokinesis. Predicted to be located in several cellular components, including cell cortex; cytoplasmic vesicle membrane; and cytoskeleton. Orthologous to human SPIRE1 (spire type actin nucleation factor 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 9_10S

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10S	NC_054388.1 (12750690..12762648)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10S	NC_030741.1 (12644779..12656682)

Chromosome 9_10S - NC_054388.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within Golgi vesicle transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within actin filament network formation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within actin filament polymerization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within actin nucleation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cleavage furrow formation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within establishment of meiotic spindle localization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within intracellular transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within polar body extrusion after meiotic divisions	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cell cortex	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle membrane	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: spire-type actin nucleation factor 1 S homeolog

Names: Eg6; spire homolog 1; spire homolog 2; spire-type actin nucleation factor 1 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093074.1 → NP_001086543.1 spire-type actin nucleation factor 1 S homeolog

See identical proteins and their annotated locations for NP_001086543.1

Status: PROVISIONAL

Source sequence(s)

BC076780

UniProtKB/TrEMBL

A0A974BT98, Q6DFF8

Related

ENSXLAP00005092483.1, ENSXLAT00005094166.1

Conserved Domains (2) summary

cd15748
Location:500 → 532

FYVE_SPIR; FYVE-related domain found in Spir proteins, Spire1 and Spire2

cl21453
Location:13 → 190

PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

12750690..12762648

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041577791.1 → XP_041433725.1 spire-type actin nucleation factor 1 S homeolog isoform X1

UniProtKB/TrEMBL

A0A8J1LYB1

Conserved Domains (2) summary

cd15748
Location:503 → 535

FYVE_SPIR; FYVE-related domain found in Spir proteins, Spire1 and Spire2

cl21453
Location:13 → 185

PKc_like; Protein Kinases, catalytic domain