parp2.S poly(ADP-ribose) polymerase 2 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: parp2.S
Official Full Name: poly(ADP-ribose) polymerase 2 S homeolog
Primary source: Xenbase:XB-GENE-1001705
Locus tag: XELAEV_18010324mg
See related: EnsemblRapid:ENSXLAG00005011749
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: parp2; adprtl2
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 1S

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (132474156..132497088)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (116987313..117009077)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables NAD+-protein poly-ADP-ribosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables nucleotidyltransferase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within double-strand break repair	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein poly-ADP-ribosylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: poly(ADP-ribose) polymerase 2 S homeolog

Names: ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2; poly (ADP-ribose) polymerase 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001093066.1 → NP_001086535.1 poly(ADP-ribose) polymerase 2 S homeolog

See identical proteins and their annotated locations for NP_001086535.1

Status: PROVISIONAL

Source sequence(s)

BC076765

UniProtKB/TrEMBL

Q6DFH2

Conserved Domains (3) summary

cd08003
Location:81 → 183

WGR_PARP2_like; WGR domain of poly(ADP-ribose) polymerases

cd01437
Location:206 → 551

parp_like; Poly(ADP-ribose) polymerase (parp) catalytic domain catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a ...

pfam00644
Location:340 → 552

PARP; Poly(ADP-ribose) polymerase catalytic domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

132474156..132497088

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041575536.1 → XP_041431470.1 poly(ADP-ribose) polymerase 2 S homeolog isoform X2

UniProtKB/TrEMBL

A0A8J1LRW0

Conserved Domains (2) summary

smart00678
Location:25 → 89

WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis

PLN03124
Location:68 → 627

PLN03124; poly [ADP-ribose] polymerase; Provisional
XM_018237386.2 → XP_018092875.1 poly(ADP-ribose) polymerase 2 S homeolog isoform X1

UniProtKB/TrEMBL

A0A1L8HPV8, A0A974DVN4

Related

ENSXLAP00005034292.1, ENSXLAT00005035175.1