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XPNPEP2 X-prolyl aminopeptidase 2 [ Sus scrofa (pig) ]

Gene ID: 445538, updated on 17-Aug-2024

Summary

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Official Symbol
XPNPEP2provided by VGNC
Official Full Name
X-prolyl aminopeptidase 2provided by VGNC
Primary source
VGNC:VGNC:95001
See related
Ensembl:ENSSSCG00000012651
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Biased expression in kidney (RPKM 80.1), mixtures (RPKM 15.8) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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See XPNPEP2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
22
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) X NC_010461.5 (106333785..106363412)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) X NC_010461.4 (122102765..122131719)

Chromosome X - NC_010461.5Genomic Context describing neighboring genes Neighboring gene OCRL inositol polyphosphate-5-phosphatase Neighboring gene apelin Neighboring gene SAM and SH3 domain containing 3 Neighboring gene zinc finger DHHC-type palmitoyltransferase 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Molecular cloning and expression in COS-1 cells of pig kidney aminopeptidase P. Hyde RJ, et al. Biochem J, 1996 Oct 1. PMID 8870669, Free PMC Article
  2. Purification and amino acid sequence of aminopeptidase P from pig kidney. Vergas Romero C, et al. Eur J Biochem, 1995 Apr 1. PMID 7744038

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloaminopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
xaa-Pro aminopeptidase 2
Names
X-Pro aminopeptidase 2
aminoacylproline aminopeptidase
aminopeptidase P
mAmP
membrane-bound APP
membrane-bound AmP
membrane-bound aminopeptidase P
NP_001004048.1
XP_005673955.1
XP_013841867.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004048.1 → NP_001004048.1  xaa-Pro aminopeptidase 2 precursor

    See identical proteins and their annotated locations for NP_001004048.1

    Status: PROVISIONAL

    Source sequence(s)
    U55039
    UniProtKB/Swiss-Prot
    Q95333
    UniProtKB/TrEMBL
    A0A8D0VUM3
    Related
    ENSSSCP00000013450.4, ENSSSCT00000013832.5
    Conserved Domains (5) summary
    COG0006
    Location:229 → 600
    PepP; Xaa-Pro aminopeptidase [Amino acid transport and metabolism]
    cd01085
    Location:364 → 582
    APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
    pfam01321
    Location:53 → 183
    Creatinase_N; Creatinase/Prolidase N-terminal domain
    pfam16188
    Location:583 → 647
    Peptidase_M24_C; C-terminal region of peptidase_M24
    pfam16189
    Location:201 → 360
    Creatinase_N_2; Creatinase/Prolidase N-terminal domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010461.5 Reference Sscrofa11.1 Primary Assembly

    Range
    106333785..106363412
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005673898.3 → XP_005673955.1  xaa-Pro aminopeptidase 2 isoform X1

    See identical proteins and their annotated locations for XP_005673955.1

    UniProtKB/Swiss-Prot
    Q95333
    UniProtKB/TrEMBL
    A0A8D0VUM3
    Conserved Domains (5) summary
    COG0006
    Location:229 → 600
    PepP; Xaa-Pro aminopeptidase [Amino acid transport and metabolism]
    cd01085
    Location:364 → 582
    APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
    pfam01321
    Location:53 → 183
    Creatinase_N; Creatinase/Prolidase N-terminal domain
    pfam16188
    Location:583 → 647
    Peptidase_M24_C; C-terminal region of peptidase_M24
    pfam16189
    Location:201 → 360
    Creatinase_N_2; Creatinase/Prolidase N-terminal domain

  2. XM_013986413.2 → XP_013841867.1  xaa-Pro aminopeptidase 2 isoform X1

    UniProtKB/Swiss-Prot
    Q95333
    UniProtKB/TrEMBL
    A0A8D0VUM3
    Conserved Domains (5) summary
    COG0006
    Location:229 → 600
    PepP; Xaa-Pro aminopeptidase [Amino acid transport and metabolism]
    cd01085
    Location:364 → 582
    APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
    pfam01321
    Location:53 → 183
    Creatinase_N; Creatinase/Prolidase N-terminal domain
    pfam16188
    Location:583 → 647
    Peptidase_M24_C; C-terminal region of peptidase_M24
    pfam16189
    Location:201 → 360
    Creatinase_N_2; Creatinase/Prolidase N-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95333.1 GenPept UniProtKB/Swiss-Prot:Q95333

Gene LinkOut

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