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ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [ Sus scrofa (pig) ]

Gene ID: 445537, updated on 17-Aug-2024

Summary

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Official Symbol
ST3GAL1provided by VGNC
Official Full Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 1provided by VGNC
Primary source
VGNC:VGNC:98863
See related
Ensembl:ENSSSCG00000005943
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
SIAT4A
Expression
Ubiquitous expression in liver (RPKM 28.6), kidney (RPKM 21.8) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See ST3GAL1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
15
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 4 NC_010446.5 (7814492..7911053)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 4 NC_010446.4 (7685469..7776994)

Chromosome 4 - NC_010446.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102159040 Neighboring gene uncharacterized LOC110260216 Neighboring gene uncharacterized LOC110260217 Neighboring gene N-myc downstream regulated 1 Neighboring gene 60S ribosomal protein L17 pseudogene Neighboring gene cellular communication network factor 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Transcriptional activation of pig Galβ1,3GalNAc α2,3-sialyltransferase (pST3Gal I) gene by TGF-β1 in porcine kidney PK-15 cells. Son SW, et al. Biochem Biophys Res Commun, 2011 Oct 14. PMID 21945615
  2. Cloning and expression of the Gal beta 1, 3GalNAc alpha 2,3-sialyltransferase. Gillespie W, et al. J Biol Chem, 1992 Oct 15. PMID 1383214
  3. Structural insight into mammalian sialyltransferases. Rao FV, et al. Nat Struct Mol Biol, 2009 Nov. PMID 19820709
  4. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  5. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Names
SIAT4-A
ST3Gal I
ST3GalA.1
ST3GalI
ST3O
alpha 2,3-ST 1
beta-galactoside alpha-2,3-sialyltransferase 1
gal beta-1,3 GalNAc alpha-2,3 sialyltransferase
gal-NAc6S
monosialoganglioside sialyltransferase
sialyltransferase 4A
NP_001004047.1
XP_005662893.1
XP_005662894.1
XP_005662895.1
XP_013851917.1
XP_020944400.1
XP_020944401.1
XP_020944402.1
XP_020944403.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004047.1 → NP_001004047.1  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

    See identical proteins and their annotated locations for NP_001004047.1

    Status: PROVISIONAL

    Source sequence(s)
    M97753
    UniProtKB/Swiss-Prot
    Q02745
    UniProtKB/TrEMBL
    A0A8D1A738
    Related
    ENSSSCP00000006354.4, ENSSSCT00000006526.5
    Conserved Domains (1) summary
    pfam00777
    Location:86 → 341
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010446.5 Reference Sscrofa11.1 Primary Assembly

    Range
    7814492..7911053
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005662836.3 → XP_005662893.1  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 isoform X1

    See identical proteins and their annotated locations for XP_005662893.1

    UniProtKB/TrEMBL
    A0A4X1SP39, A0A8D1A738, F1RRV7, K7GPR8
    Conserved Domains (1) summary
    pfam00777
    Location:86 → 341
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  2. XM_013996463.2 → XP_013851917.1  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A4X1SP39, A0A8D1A738, F1RRV7, K7GPR8
    Conserved Domains (1) summary
    pfam00777
    Location:86 → 341
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  3. XM_021088743.1 → XP_020944402.1  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A4X1SP39, A0A8D1A738, F1RRV7, K7GPR8
    Conserved Domains (1) summary
    pfam00777
    Location:86 → 341
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  4. XM_021088742.1 → XP_020944401.1  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A4X1SP39, A0A8D1A738, F1RRV7, K7GPR8
    Conserved Domains (1) summary
    pfam00777
    Location:86 → 341
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  5. XM_005662838.3 → XP_005662895.1  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 isoform X1

    See identical proteins and their annotated locations for XP_005662895.1

    UniProtKB/TrEMBL
    A0A4X1SP39, A0A8D1A738, F1RRV7, K7GPR8
    Conserved Domains (1) summary
    pfam00777
    Location:86 → 341
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  6. XM_021088744.1 → XP_020944403.1  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A4X1SP39, A0A8D1A738, F1RRV7, K7GPR8
    Conserved Domains (1) summary
    pfam00777
    Location:86 → 341
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  7. XM_021088741.1 → XP_020944400.1  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A4X1SP39, A0A8D1A738, F1RRV7, K7GPR8
    Conserved Domains (1) summary
    pfam00777
    Location:86 → 341
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  8. XM_005662837.3 → XP_005662894.1  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 isoform X1

    See identical proteins and their annotated locations for XP_005662894.1

    UniProtKB/TrEMBL
    A0A4X1SP39, A0A8D1A738, F1RRV7, K7GPR8
    Conserved Domains (1) summary
    pfam00777
    Location:86 → 341
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02745.1 GenPept UniProtKB/Swiss-Prot:Q02745

Gene LinkOut

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