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ATP6V1A ATPase H+ transporting V1 subunit A [ Sus scrofa (pig) ]

Gene ID: 445531, updated on 17-Aug-2024

Summary

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Official Symbol
ATP6V1Aprovided by VGNC
Official Full Name
ATPase H+ transporting V1 subunit Aprovided by VGNC
Primary source
VGNC:VGNC:85669
See related
Ensembl:ENSSSCG00000011916
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
ATP6A1; ATP6V1A1
Annotation information
Annotation category: partial on reference assembly
Expression
Broad expression in kidney (RPKM 71.0), lung (RPKM 33.9) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (146128664..146165269, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (155713931..155750535, complement)

Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 23 Neighboring gene GRAM domain containing 1C Neighboring gene N-alpha-acetyltransferase 50, NatE catalytic subunit Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene upstream transcription factor family member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Sequence analysis of the catalytic subunit of H(+)-ATPase from porcine renal brush-border membranes. Sander I, et al. Biochim Biophys Acta, 1992 Nov 23. PMID 1420264

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables proton-transporting ATPase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ATP metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of proton-transporting V-type ATPase, V1 domain IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
V-type proton ATPase catalytic subunit A
Names
H+ ATPase
V-ATPase 69 kDa subunit
V-ATPase subunit A
Vacuolar ATP synthase catalytic subunit A
vacuolar proton pump subunit alpha
NP_001004042.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004042.1 → NP_001004042.1  V-type proton ATPase catalytic subunit A

    See identical proteins and their annotated locations for NP_001004042.1

    Status: PROVISIONAL

    Source sequence(s)
    X62338
    UniProtKB/Swiss-Prot
    Q29048
    Related
    ENSSSCP00000052009.1, ENSSSCT00000039822.2
    Conserved Domains (4) summary
    cd01134
    Location:86 → 458
    V_A-ATPase_A; V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi ...
    TIGR01042
    Location:18 → 610
    V-ATPase_V1_A; V-type (H+)-ATPase V1, A subunit
    pfam00306
    Location:476 → 618
    ATP-synt_ab_C; ATP synthase alpha/beta chain, C terminal domain
    pfam02874
    Location:22 → 84
    ATP-synt_ab_N; ATP synthase alpha/beta family, beta-barrel domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

    Range
    146128664..146165269 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q29048.2 GenPept UniProtKB/Swiss-Prot:Q29048

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